Copaiba Oil-Loaded Polymeric Nanocapsules: Production and In Vitro Biosafety Evaluation on Lung Cells as a Pre-Formulation Step to Produce Phytotherapeutic Medicine [PDF]
Copaiba oil has been largely used due to its therapeutic properties. Nanocapsules were revealed to be a great nanosystem to carry natural oils due to their ability to improve the bioaccessibility and the bioavailability of lipophilic compounds.
Victor M. Rodrigues +9 more
doaj +4 more sources
Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis (EAE) [PDF]
Experimental autoimmune encephalomyelitis (EAE) is a murine autoimmune disease used to study multiple sclerosis. We have investigated the immunomodulatory effects of copaiba oil (100, 50 and 25 µg/mL) on NO, H2O2, TNF-α, IFN-γ and IL-17 production in ...
Débora S. Dias +6 more
doaj +4 more sources
Chemical Characterization and Quality Assessment of Copaiba Oil-Resin Using GC/MS and SFC/MS [PDF]
In recent years, the popularity of copaiba oil-resin has increased worldwide due to its medicinal value and wide applications in industry. Despite its popularity, the oil has not been standardized by industry or regulatory agencies.
Joseph Lee +5 more
doaj +4 more sources
Effects of Copaiba oil in the healing process of urinary bladder in rats [PDF]
Introduction The appropriate closure of the urinary bladder is important to many urologic procedures to avoid the formation of fistulas and strictures by excessive fibrosis. This paper presents the alterations in the bladder healing process of rats after
Denilson José Silva Feitosa Junior +5 more
doaj +6 more sources
Effects of copaiba oil on dermonecrosis induced by Loxosceles intermedia venom [PDF]
Background: Accidents caused by spiders of the genus Loxosceles constitute an important public health problem in Brazil. The venom of Loxosceles sp induces dermonecrosis at the bite site and systemic disease in severe cases. Traditional medicine based on
Mara Fernandes Ribeiro +8 more
doaj +6 more sources
(E)-2,6,10-Trimethyldodec-8-en-2-ol: An Undescribed Sesquiterpenoid from Copaiba Oil [PDF]
The use of copaiba oil has been reported since the 16th century in Amazon traditional medicine, especially as an anti-inflammatory ingredient and for wound healing.
Mohammed F. Hawwal +6 more
doaj +2 more sources
Chemical Profiling and Biological Activity of Copaiba Oil-Resin Samples and Development of HPLC-DAD Method for the Analysis of β-Caryophyllene. [PDF]
ABSTRACT The Copaifera species are traditionally used for their anti‐inflammatory, antiseptic and healing properties. The objective of this study was to compare the chromatographic profiles of seven samples of copaiba oil‐resin with respect to chromatographic and physicochemical properties and to evaluate their biological activities.
Graça GAP +13 more
europepmc +2 more sources
Copaiba Oil-Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats. [PDF]
ABSTRACT Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP).
Nazário RMF +11 more
europepmc +2 more sources
Medicinal Plants for Acne Vulgaris: An Evidence-Based Review of Treatments Promoted by Social Media. [PDF]
ABSTRACT Background Acne vulgaris refers to a chronic inflammatory state of the pilosebaceous follicles that affects the majority of adolescents. Treatments encompass topical agents and systemic therapies. Nowadays, we encounter a growing tendency to use herbal remedies, which raises concerns about misinformation disseminated by digital platforms.
Parvizi MM +6 more
europepmc +2 more sources
Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues [PDF]
Background The regeneration of integrity and tissue homeostasis after injury is a fundamental property and involves complex biological processes fully dynamic and interconnected.
Francisco Bruno Teixeira +6 more
doaj +2 more sources

