Results 121 to 130 of about 629,305 (401)

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

Advanced Intelligent Discovery, EarlyView.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren, Bohao Liu, Zhiyuan Qu, Xue Jiang, Heng Zhao, Danyao Qu, Ruizhi Ning, Chen Su, Taoping Liu, Guangjian Zhang, Weiwei Wu   +10 more
wiley   +1 more source

Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD [PDF]

, 2014
Dirkje S Postma,1 Nicolas Roche,2 Gene Colice,3 Elliot Israel,4 Richard J Martin,5 Willem MC van Aalderen,6 Jonathan Grigg,7 Anne Burden,8 Elizabeth V Hillyer,8 Julie von Ziegenweidt,8 Gokul Gopalan,9 David Price8,10 1University of Groningen, Department ...
Burden, A, Colice, G, Gopalan, G, Grigg, J, Hillyer, EV, Israel, E, Martin, RJ, Postma, DS, Price, D, Roche, N, van Aalderen, WMC, von Ziegenweidt, J   +11 more
core   +6 more sources

Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis

International Journal of COPD, 2018
Rationale COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited.
Georgios Ntritsos, J. Franek, L. Belbasis, M. Christou, G. Markozannes, P. Altman, R. Fogel, T. Sayre, E. Ntzani, E. Evangelou   +9 more
semanticscholar   +1 more source

Autonomous Recognition of Retained Secretions in Central‐Airway Based on Deep Learning for Adult Patients Receiving Invasive Mechanical Ventilation

Advanced Intelligent Systems, EarlyView.
This work presents a deep learning model to autonomously recognize and classify the secretion retention into three levels for patients receiving invasive mechanical ventilation, achieving 89.08% accuracy. This model can be implemented to ventilators by edge computing, whose feasibility is approved.
Shuai Wang, Zhuoran Xiao, Meng Wang, Jianchao Li, Chunjing Tao, Jiangzhen Guo, Yubo Fan   +6 more
wiley   +1 more source

Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD

European Respiratory Review, 2019
Chronic obstructive pulmonary disease (COPD) is currently the third most common cause of global mortality. Acute exacerbations of COPD frequently necessitate hospital admission to enable more intensive therapy, incurring significant healthcare costs ...
D. Linden, H. Guo-Parke, P. Coyle, D. Fairley, D. McAuley, C. Taggart, J. Kidney   +6 more
semanticscholar   +1 more source

Indices and COPD [PDF]

Multidisciplinary Respiratory Medicine, 2010
The paper by Inal-Ince and colleagues (pag. 162-167) examines fatigue in chronic obstructive pulmonary disease (COPD) relating it to multi dimensional in- dices of overall disease severity, BODE and SAFE. It is the selection of these indices that will be examined in this Editorial.
openaire   +4 more sources

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen, Eveliina Brandt, Kaisa Kettunen, Outi Elomaa, Sirpa Kivirikko, Leila Jeskanen, Katriina Lappalainen, Nelli Sjöblom, Juha Kere, Katariina Hannula‐Jouppi, Liisa Harjama   +10 more
wiley   +1 more source

The efficacy of psychologically based interventions to improve anxiety, depression and quality of life in COPD: a systematic review and meta-analysis [PDF]

, 2012
This article comprises a systematic review and meta-analysis looking at the efficacy of psychological intervention in improving anxiety, depression and quality of life in respiratory disease.Objective: To systematically evaluate the efficacy of ...
Adams, Amy Baraniak, Burgess, Cohen, Coventry, Coventry, Cully, David Sheffield, de Godoy, De Godoy, Eiser, Emery, Gift, Healthcare Commission, Hynninen, Jacobs, Karadag, Kunik, Kunik, Lacasse, Lamers, Lisansky, Lolak, Miravitlles, Moullec, Narsavage, National Institute for Clinical Excellence, Norweg, Oakley, Peytremann-Bridevaux, Pull, Punekar, Pye, Ries, Rose, Rosser, Salman, Salvi, Sassi-Dambron, Scherer, Schoo, Sirey, Stanley, Sutton, van Ede, Wagena, Wu, Yohannes   +47 more
core   +2 more sources

Inhaled corticosteroids in COPD: friend or foe?

European Respiratory Journal, 2018
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can result in clear clinical benefits in some patients (“friend”) but can be ...
A. Agustí, L. Fabbri, Dave Singh, J. Vestbo, B. Celli, F. Franssen, K. Rabe, A. Papi   +7 more
semanticscholar   +1 more source

Management of COPD [PDF]

Thorax, 2003
In their recent review1 MacNee and Calverley provided an excellent summary of the management of COPD. However, I question their assertions regarding domiciliary oxygen. Citing the work of Gorecka et al 2 and Chaouat et al ,3 it is stated that domiciliary oxygen does not benefit patients with relatively mild hypoxaemia or isolated nocturnal desaturation.
openaire   +2 more sources