Summary This pilot randomised feasibility trial evaluated the feasibility and acceptability of early, intensive home‐based pulmonary rehabilitation (PR) and high‐flow nasal oxygen (HFO) during exercise in patients with exertional hypoxaemia post‐hospitalisation. Early home‐based PR was feasible and safe.
Yingjuan Mok +11 more
wiley +1 more source
Association of MiR-27a-5p with chronic obstructive pulmonary disease and its role in human bronchial epithelial cell injury: A case-control and in vitro experimental study. [PDF]
Wang J, Zhang P, Qin Y.
europepmc +1 more source
Identifying impaired lifetime lung function trajectories is key to identifying the preclinical phase of COPD (Pre‐COPD) or prognosis of COPD. We have identified that some circulating established COPD biomarkers differ across ‘pre‐COPD’ lung function trajectories, suggesting that some COPD‐specific pathobiological processes, including inflammation, are ...
Dinh S. Bui +23 more
wiley +1 more source
Critical Biological Functions and Clinical Implications of Epigenetic-Related Candidate Biomarkers in Chronic Obstructive Pulmonary Disease: Integrated Machine Learning Screening and Basic Experimental Validation. [PDF]
Xie J, Huang L, Chen X, Wang X.
europepmc +1 more source
ABSTRACT Background and Objective People with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) experience chronic breathlessness and reduced quality of life (QOL). Specialised singing programs for people with lung disease may improve QOL and symptoms.
Natasha Smallwood +8 more
wiley +1 more source
Peripheral Blood Inflammatory Markers and Immune Cell Profiles in Smokers With and Without COPD. [PDF]
Lu W +10 more
europepmc +1 more source
Burden of COPD and lung cancer attributable to household air pollution in Morocco: a secondary analysis using population attributable fractions. [PDF]
El Harch I +4 more
europepmc +1 more source
Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi +23 more
wiley +1 more source
Correlation between intestinal flora characteristics and immune function in COPD patients treated with non-invasive ventilator and its value in predicting ventilator-associated pneumonia: A prospective study. [PDF]
Liu Y, Liu C, Huang C, Pang L.
europepmc +1 more source

