Results 271 to 280 of about 629,305 (401)

Effects of geranylgeranylacetone on diastolic and microvascular function in patients with heart failure with a preserved ejection fraction: A phase 2, randomized, placebo‐controlled, crossover trial

European Journal of Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a major healthcare burden with limited treatment options. Geranylgeranylacetone (GGA) has been shown to improve myocardial compliance and endothelial function in preclinical models.
Soufiane Nassiri, Geert H.D. Voordes, Loek van Heerebeek, Daniël H. van Raalte, Marianne C. Verhaar, Daan J. Touw, Merle M. Krebber, Dirk J. Duncker, Etto C. Eringa, M. Louis Handoko, Adriaan A. Voors, on behalf of the RECONNEXT Consortium   +11 more
wiley   +1 more source

Telerehabilitation with breathing exercises as a strategy to improve functional capacity of patients with chronic obstructive pulmonary disease: randomized clinical trial. [PDF]

Einstein (Sao Paulo)
de Toledo KFT, Bertolini SMMG, de Mello ST, Rodrigues Junior GM.   +3 more
europepmc   +1 more source

Acute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides

European Journal of Heart Failure, EarlyView.
Cancer patients presenting to the emergency department ED with dyspnoea. Among 2153 patients presenting to the ED with dyspnea, 473 (22.0%) had an active or past cancer. Acute heart failure (AHF) was the most common final diagnosis in both groups. Pneumonia and cancer‐related dyspnoea were more common in cancer patients.
Paolo Bima, Desirée Wussler, Pedro Lopez‐Ayala, Maria Belkin, Albina Nowak, Xueting Lin, Ivo Strebel, Fabiana Sgueglia, Eleni Michou, Androniki Papachristou, Laureve Chollet, Codruta Popescu, Nikola Kozhuharov, Samyut Shrestha, Gabriela Kuster, Katharina Rentsch, Arnold Von Eckardstein, Mascha Binder, Felix Mahfoud, Tobias Breidthardt, Christian Mueller   +20 more
wiley   +1 more source

The prevalence of chronic obstructive pulmonary disease in high-altitude areas of China: a systematic review and meta-analysis. [PDF]

J Thorac Dis
Wei S, Liu X.
europepmc   +1 more source

Characteristics and outcomes of patients with heart failure and history of malignancy: Data from Swedish Heart Failure Registry and the National Cancer Register

European Journal of Heart Failure, EarlyView.
Prevalence and predictors of, and outcome associated with history of cancer in patients with heart failure. AF, atrial fibrillation; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CV, cardiovascular; DM, diabetes mellitus; EF, ejection fraction; GDMT, guideline‐directed medical therapy; GI, gastrointestinal; Hb, haemoglobin; HF ...
Pietro Ameri, Paolo Costa, Lina Benson, Davide Stolfo, Nabil V. Sayour, Charlotta Ljungman, Javed Butler, Stefan D. Anker, Nicolas Girerd, Kalliopi Keramida, Gerasimos Filippatos, Lars H. Lund, Felix Lindberg, Gianluigi Savarese   +13 more
wiley   +1 more source

Lung tissue T cells are activated in chronic obstructive pulmonary disease with non-small cell lung cancer patients. [PDF]

Sci Rep
Tone M, Isono T, Yamamoto Y, Takeda Y, Shintani Y, Kumanogoh A, Wada H, Iwahori K.   +7 more
europepmc   +1 more source

Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis

European Journal of Heart Failure, EarlyView.
Abstract Aims Age‐associated clonal haematopoiesis of indeterminate potential (CHIP) has been linked to increased incidence and worse prognosis of chronic heart failure (CHF). CHIP arises from somatic mutations in haematopoietic stem and progenitor cells. Mosaic loss of Y chromosome (LOY), the most common somatic mutation in male blood cells, increases
Sebastian Cremer, Moritz von Scheidt, Klara Kirschbaum, Lukas Tombor, Silvia Mas‐Peiro, Wesley Abplanalp, Tina Rasper, Akshay Ware, Andrin Schuff, Alexander Berkowitsch, Johannes Krefting, David Leistner, Heribert Schunkert, Thimoteus Speer, Stefanie Dimmeler, Andreas Michael Zeiher   +15 more
wiley   +1 more source

To Breathe or Not to Breathe: Spontaneous Ventilation During Thoracic Surgery in High-Risk COPD Patients-A Feasibility Study. [PDF]

J Clin Med
Szarvas M, Fabo C, Demeter G, Oszlanyi A, Vaida S, Furak J, Szabo Z.   +6 more
europepmc   +1 more source

Epigenetic targets for lung diseases [PDF]

, 2019
Lahousse, Lies
core   +2 more sources

Management of patients with heart failure at high risk of hyperkalaemia: The CARE‐HK in HF registry

European Journal of Heart Failure, EarlyView.
Primary results of the CARE‐HK in HF registry. ACEI, angiotensin‐converting enzyme inhibitor; ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor–neprilysin inhibitor; CI, confidence interval; eGFR, estimated glomerular filtration rate; HF, heart failure; HK, hyperkalaemia; HR, hazard ratio; MRA, mineralocorticoid receptor antagonist; RASi,
Stephen J. Greene, Andrew J. Sauer, Michael Böhm, Biykem Bozkurt, Javed Butler, John G.F. Cleland, Andrew J.S. Coats, Nihar R. Desai, Diederick E. Grobbee, Ellie Kelepouris, Fausto Pinto, Giuseppe Rosano, Victoria Donachie, Solenn Fabien, Sandra Waechter, Maria G. Crespo‐Leiro, Martin Hülsmann, Tibor Kempf, Otmar Pfister, Anne‐Catherine Pouleur, Manish Saxena, Martin Schulz, Maurizio Volterrani, Stefan D. Anker, Mikhail N. Kosiborod   +24 more
wiley   +1 more source