Results 351 to 360 of about 629,305 (401)

The impact of COPD and smoking history on the severity of COVID‐19: A systemic review and meta‐analysis

open access: yesJournal of Medical Virology, 2020
Comorbidities are associated with the severity of coronavirus disease 2019 (COVID‐19). This meta‐analysis aimed to explore the risk of severe COVID‐19 in patients with pre‐existing chronic obstructive pulmonary disease (COPD) and ongoing smoking history.
Qianwen Zhao, Meng Meng, Rahul Kumar
exaly   +2 more sources

Progress in the mechanism and targeted drug therapy for COPD

open access: yesSignal Transduction and Targeted Therapy, 2020
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis characterised by long-term breathing problems and poor airflow. The prevalence of COPD has increased over the last decade and the drugs most commonly used to treat it ...
Atsushi Fukunaga
exaly   +2 more sources

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

open access: yesNature Communications, 2019
Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid peroxidation in association with free iron-mediated Fenton reactions.
Masahiro Yoshida   +2 more
exaly   +2 more sources

COPD-Lite, COPD-Hard, or COPD-for-What?

American Journal of Respiratory and Critical Care Medicine, 2011
not ...
de Marco R, Accordini S, Marcon A
openaire   +1 more source

COPD is not COPD is not ALLERGY

Wiener klinische Wochenschrift, 2009
Chronic obstructive pulmonary disease (COPD) is still a poorly understood disease. Its pathogenesis is excitingly complex and has systemic consequences caused not only by increased production of certain cytokines but also by neurohumoral activation, chronic bacterial infection, muscle wasting and cachexia. Asthma and COPD have many overlapping clinical
openaire   +2 more sources

The diagnosis of COPD

Wiener Medizinische Wochenschrift, 2005
Lung function testing (spirometry) is crucial for the diagnosis of COPD, as irreversible airway obstruction is the main feature of chronic airway inflammation. Spirometry not only is essential in making the diagnosis but also in grading the disease according to FEV1 measurements.
Sylvia, Hartl, Otto C, Burghuber
openaire   +2 more sources

COPD

Nursing Standard, 2015
Essential facts Chronic obstructive pulmonary disease (COPD) covers a number of lung conditions, including emphysema and chronic bronchitis. People with COPD have lung damage that is not fully reversible. These conditions kill about 30,000 people a year in the UK.
openaire   +2 more sources

Biomarkers in COPD

Clinics in Chest Medicine, 2014
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that cannot be described by the severity of airflow limitation (forced expiratory volume in the first second of expiration) only. Other measures are needed in clinical practice to assess patients, predict their risk, guide their treatment, and assess their response to it.
Alvar, Agusti, Don D, Sin
openaire   +2 more sources

COPD Phenotyping

Respiratory Care, 2023
COPD is a heterogeneous condition, the onset and trajectory of which is influenced not only by tobacco exposure but also an individual's genetics and the exposures they accumulate over their life course. In such a complex chronic disease, phenotyping individuals based on similar clinical or molecular characteristics can aid in guiding appropriate ...
openaire   +2 more sources

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