Results 31 to 40 of about 900,038 (245)

Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Letter]

Clinical Epidemiology, 2022
Morten Baltzer Houlind,1–4 Esben Iversen,1 Baker Nawfal Jawad,1 Thomas Kallemose,1 Mads Hornum5,6 1Department of Clinical Research, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark; 2The Capital Region Pharmacy, Herlev,
Houlind MB, Iversen E, Jawad BN, Kallemose T, Hornum M   +4 more
doaj  

Selective Catalytic Production of Urea: Unravelling the Pairwise Competition on p‐d Alloy Catalysts

Advanced Science, EarlyView.
Unraveling the complicated competition in urea electrosynthesis, this work investigates asymmetric p‐d alloys. We establish two stage‐specific descriptors, Anchoring Affinity and Coupling Propensity, to elegantly quantify thermodynamic bottlenecks.
Qingchao Fang, Yun Han, Md Tarikal Nasir, Fuyong Qin, Wanhu Tian, Hanqing Yin, Aijun Du   +6 more
wiley   +1 more source

Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Response to Letter]

Clinical Epidemiology, 2022
Benjamin Skov Kaas-Hansen,1–3 Cristina Leal Rodríguez,2 Davide Placido,2 Hans-Christian Thorsen-Meyer,2,4 Anna Pors Nielsen,2 Nicolas Dérian,5 Søren Brunak,2 Stig Ejdrup Andersen1 1Clinical Pharmacology Unit, Zealand University
Kaas-Hansen BS, Leal Rodríguez C, Placido D, Thorsen-Meyer HC, Nielsen AP, Dérian N, Brunak S, Andersen SE   +7 more
doaj  

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

Messages from Copenhagen: Assessments of the Accord and Implications for the EU. CEPS ECP Report No. 9, April 2010 [PDF]

, 2010
The aim of this paper is to review major assessments of the Copenhagen Accord with a focus on what it will ultimately deliver, especially within the context of the economic crisis.
Alessi, Monica, Georgiev, Anton, Egenhofer, Christian.   +2 more
core  

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Novel Genetic Causes of Gastrointestinal Polyposis Syndromes

The Application of Clinical Genetics, 2021
Anne Marie Jelsig,1 Anna Byrjalsen,1 Majbritt Busk Madsen,2 Tine Plato Kuhlmann,3 Thomas van Overeem Hansen,1 Karin AW Wadt,1,4 John Gásdal Karstensen4,5 1Department of Clinical Genetics, University Hospital of Copenhagen, Copenhagen, Denmark; 2Center ...
Jelsig AM, Byrjalsen A, Busk Madsen M, Kuhlmann TP, van Overeem Hansen T, Wadt KAW, Karstensen JG   +6 more
doaj  

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

Consumers' Willingness to Pay a Premium for Climate‐Friendly Food Production: The Role of Production Method Information and Social Norms

Agribusiness, EarlyView.
ABSTRACT This study examines whether information about production methods and social norms can increase consumers' willingness to pay (WTP) a price premium for food produced using climate‐friendly farming methods. A randomized survey experiment was conducted with 1568 respondents across Denmark, Lithuania, and Spain, who were assigned to one of four ...
Kassa Tarekegn Erekalo, Tove Christensen, Sigrid Denver, Marilena Gemtou, Spyros Fountas, Søren Marcus Pedersen   +5 more
wiley   +1 more source