Results 181 to 190 of about 5,906 (213)
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Journal of Cardiovascular Medicine, 2013
Copeptin, the C-terminal part of the prohormone of vasopressin (AVP), is released together with AVP in stoichiometric concentrations reflecting an individual's stress level. Copeptin has come to be regarded as an important marker for identifying high-risk patients and predicting outcomes in a variety of diseases.
Beata, Morawiec, Damian, Kawecki
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Copeptin, the C-terminal part of the prohormone of vasopressin (AVP), is released together with AVP in stoichiometric concentrations reflecting an individual's stress level. Copeptin has come to be regarded as an important marker for identifying high-risk patients and predicting outcomes in a variety of diseases.
Beata, Morawiec, Damian, Kawecki
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Vasopressin and Copeptin in Health and Disease
Reviews in Endocrine and Metabolic Disorders, 2019Arginine Vasopressin (AVP) and copeptin derive from the same precursor molecule. Due to the equimolar secretion, copeptin responds as rapidly as AVP to osmotic, hemodynamic and unspecific stress-related stimuli and both peptides show a very strong correlation.
Mirjam Christ-Crain
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2016
Heart failure (HF) is one of the most common causes of hospitalization and mortality in the modern Western world and an increasing proportion of the population will be affected by HF in the future. Although HF management has improved quality of life and prognosis, mortality remains very high despite therapeutic options. Medical management consists of a
Louise, Balling, Finn, Gustafsson
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Heart failure (HF) is one of the most common causes of hospitalization and mortality in the modern Western world and an increasing proportion of the population will be affected by HF in the future. Although HF management has improved quality of life and prognosis, mortality remains very high despite therapeutic options. Medical management consists of a
Louise, Balling, Finn, Gustafsson
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Copeptin as a Biomarker in Heart Failure
Biomarkers in Medicine, 2014Increased neurohormonal activation is a key feature of heart failure (HF). Copeptin is a surrogate marker for proarginine vasopressin and the prognostic value of copeptin has been reported for multiple disease states of both nonvascular and cardiovascular etiology.
Louise, Balling, Finn, Gustafsson
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Copeptin: Utility in Paediatric Patients with Hyponatraemia
Hormone Research in Paediatrics, 2021<b><i>Introduction:</i></b> Copeptin concentrations are a useful component of the diagnostic workup of paediatric patients with polyuria and polydipsia, but the value of measuring copeptin in patients with hyponatraemia is less clear.
Rachel L. Boal +5 more
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Copeptin as a Diagnostic Biomarker for Sepsis-Related Deaths
Peptides, 2014 Copeptin has been shown to increase in patients with sepsis, severe sepsis and septic shock. In the study herein described, copeptin was measured in a series of sepsis-related fatalities and control cases that underwent medico-legal investigations.
Marc Augsburger, Cristian Palmiere
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Copeptin is increased in resistant hypertension
Journal of Hypertension, 2016The participation of vasopressin in the mechanisms of resistant hypertension is unclear. We compared plasma copeptin concentration, a surrogate marker for vasopressin secretion, between patients with resistant hypertension and those with controlled blood pressure (CBP), in a post hoc analysis of the Prise en charge de l'Hypertension Artérielle ...
Mendes, Margarida +9 more
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Copeptin as a Biomarker in Cardiac Disease
Current Topics in Medicinal Chemistry, 2013The introduction of biochemical biomarkers in the evaluation of patients with cardiovascular disease has led to practice-changing advancements in the way these patients are diagnosed and managed. Measurements of cardiac troponins or brain-type natriuretic peptide (BNP) and its precursor, N-terminal brain-type natriuretic peptide (NT-proBNP), have ...
Georgios, Giannopoulos +7 more
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Copeptin in Preeclampsia Development
Current Women s Health Reviews, 2019Background: Preeclampsia complicates 2-8% of all pregnancies worldwide and is one of the leading causes of maternal and neonatal morbidity and mortality. It occurs after the 20th week of gestation and is characterized by high blood pressure, proteinuria or end-organ disease.
Nalini Govender +2 more
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Copeptin: Pathophysiology and potential clinical impact
Advances in Medical Sciences, 2015Copeptin, a C-terminal part of the precursor pre-provasopressin is a novel biomarker of arginine-vasopressin (AVP) system. Measurements of AVP concentration are not used in clinical practice because of technical difficulties. Copeptin is synthesized in stoichiometric ratio with AVP, hence it reflects vasopressin concentration in human plasma and serum.
Łukaszyk, Ewelina, Jolanta Małyszko
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