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A State‐Gated Metallo‐DNAzyme Framework Programs Tumor Stress Vulnerability Through Metabolic Licensing

open access: yesAdvanced Science, EarlyView.
A tumor‐state‐gated metallo‐DNAzyme framework integrates miR‐21/APE1‐responsive GLUT1 silencing with Ca/Cu‐partitioned metal–nucleic acid assembly and cystine loading. The framework first weakens glucose‐dependent metabolic buffering and then amplifies copper‐ and disulfide‐associated stress, converting tumor metabolic adaptation into programmable ...
Xiaodong Ma   +8 more
wiley   +1 more source

Copper–NHC Complexes in Catalysis [PDF]

open access: yesCoordination Chemistry Reviews, 2015
Abstract Although the chemistry of copper has a long history [1a-d] , the relatively recent discovery of N-heterocyclic carbene (NHC) as transition-metal supporting ligands has permitted novel vistas to be explored in copper reactivity and catalysis [1e,f] .
Fady Nahra   +2 more
exaly   +4 more sources
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Fullerenes make copper catalysis better

Science, 2022
Ethylene glycol can be reliably produced by mild hydrogenation of dimethyl ...
Gravel, Edmond, Doris, Eric
openaire   +4 more sources

Copper(II) Catalysis of Water Oxidation

Angewandte Chemie International Edition, 2012
Copper leads to a breakup: simple Cu(II) salts are shown to be highly reactive as water oxidation electrocatalysts in neutral to weakly basic aqueous buffer solutions of CO(2)/HCO(3)(-)/CO(3)(2-) or HPO(4)(2-)/PO(4)(3-). Coordination to the buffer anions under these conditions prevents the precipitation of Cu(OH)(2), CuCO(3), or Cu(3)(PO(4))(2) and ...
Zuofeng, Chen, Thomas J, Meyer
openaire   +2 more sources

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