Results 231 to 240 of about 207,162 (296)

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +2 more sources

Ingestion of bedding material as a cause of acute copper sulfate poisoning in turkey poults. [PDF]

open access: yesPoult Sci, 2019
Giergiel M   +5 more
europepmc   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

open access: yesAngewandte Chemie, EarlyView.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte   +2 more
wiley   +2 more sources

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

open access: yesAngewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne   +22 more
wiley   +1 more source

Asymmetric Fe–Te Pairs Enhance Peroxymonosulfate Activation via Surface‐Bound Hydroxyl Radicals Pathways

open access: yesAngewandte Chemie International Edition, EarlyView.
An asymmetric Fe–Te dual‐atom pair directs peroxymonosulfate activation toward long‐lived surface‐bound hydroxyl radicals through strong p–d hybridization. The resulting electronic asymmetry enables efficient pharmaceutical degradation and reveals a metal–metalloid pairing strategy for steering reactive oxygen species pathways in advanced oxidation ...
Xuheng Li   +6 more
wiley   +1 more source

The Effect of Demineralization on Coal Functional Group Pyrolysis: Rank‐Dependent Dual Mechanisms of Structural Reorganization and Mineral Catalysis

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Coal pyrolysis, as a key thermochemical conversion process, is significantly influenced by inherent minerals, yet their role across different coal ranks remains inadequately understood. This study investigates the effect of acid‐washing (demineralization) on the thermal decomposition of six functional groups (aliphatic C–H, aromatic C–H/C=C, C=
Zhiyuan Niu   +4 more
wiley   +1 more source

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