Results 131 to 140 of about 1,208,876 (310)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The Copy Theory of Control and the Analysis of Finite Control
LanguagesUnder the Markovian property of derivations the history of the derivation is not preserved in the current state, hence chains cannot be read off it.
Maria Rita Manzini, Anna Roussou
doaj +1 more source
Le scintillement de l'épilinguistique [PDF]
, 2018 International ...
Bédouret-Larraburu, Sandrine +1 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Honolulu Area Metropolitan Map Series Pre-Enumeration Copy, Sheet 3, 1969 [PDF]
, 1969 Scale 1:24,000. 1 map ; 36 x 48.5 cm on sheet 47 x 61 cm. Pre-enumeration copy of census tracts for Honolulu.
United States. Bureau of the Census.
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Honolulu Area Metropolitan Map Series Pre-Enumeration Copy, Sheet 10, 1969 [PDF]
, 1969 Scale 1:24,000. 1 map ; 36 x 48.5 cm on sheet 47 x 61 cm. Pre-enumeration copy of census tracts for Honolulu.
United States. Bureau of the Census.
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source