Results 51 to 60 of about 4,483,351 (293)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Juan Carlos Onetti : La escritura con propósitos
We will consider the analysis of the writing processes in Juan Carlos Onetti’s novel Juntacadáveres(1964), focusing our work on documents, manuscripts and typescripts corrected by hand by the author himself. In the manuscripts where he drew up chapters 1
María Alejandra Alí
doaj +1 more source
Nine Inch Nails have just released a new single; In addition to the usual formats, “The Hand That Feeds” was available for free download in Garageband format. Trent Reznor explained, “For quite some time I’ve been interested in the idea of allowing you the ability to tinker around with my tracks – to create remixes ...
openaire +1 more source
Stochastic Gene Expression in Single Gene Oscillator Variants [PDF]
It is infeasible to understand all dynamics in cell, but we can aim to understand the impact of design choices under our control. Here we consider a single gene oscillator as a case study to understand the influence of DNA copy number and repressor ...
Bennett, Matthew R. +4 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Empreintes, moulages, traces : d’Orient en Occident
Ruins, in the Latin and Greek acceptation of the term, are what is left of a monument or a site which was inhabited by men. Vestiges are related to ruins, but with a different meaning. Vestigia in Latin signifies footprints, just as ichné in Greek refers
Alain Schnapp
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
‘Palimpsesto’ cinematográfico: rescribiendo y releyendo The Tempest de William Shakespeare
Resumen: La reproducción audiovisual del canon literario en el ámbito anglonorteamericano implica un desafío de gran calibre ante crítica, académicos y público, resuelto con originalidad creativa y solvencia tecnológica en la adaptación cinematográfi ca ...
Francisco José Cortés Vieco
doaj +1 more source
Keeping our children safe around dogs: Guidelines for safe interaction between children and pet dogs - English [PDF]
Obtain a copy of the children’s leaflet (about 5-6yrs) in English from https://hdl.handle.net/10289/968. Obtain a copy of the children’s leaflet (about 5-6yrs) in Te Reo Maori from https://hdl.handle.net/10289/975. Obtain a copy of the children’s
Carter, Jennifer, Swain, David
core +1 more source

