Results 61 to 70 of about 4,483,351 (293)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A statutory compensation model for AI training based on the copy levies payment framework [PDF]

open access: yesAnnales Scientia Politica
The article addresses the lack of adequate legal mechanisms regulating the use of copyrighted works in the training of artificial intelligence (AI) algorithms, particularly in the context of copyright law.
Andrzej Madera
doaj  

Spectral Consciousness in Post-9/11 American Poetry [PDF]

open access: yes, 2017
After presenting an overview of scholarship on post-9/11 American poetry, my article focuses on a group of largely neglected post-9/11 poems, which deal with spectral consciousness and hallucinatory experiences. These poems not only challenge a number of
Joydeep Chakraborty
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conforming to the Prototype: The Virgin of Copacabana and her Copies, between Lake Titicaca and Madrid

open access: yesIntrecci d'arte
This article examines the dissemination of the image of the Virgin of Copacabana, a prominent Marian image in the Andean Plateau (Altiplano) on the shores of Lake Titicaca.
Lucía Querejazu Escobari
doaj   +1 more source

Genericity of Fr\'echet smooth spaces [PDF]

open access: yes, 2011
If a separable Banach space contains an isometric copy of every separable reflexive Fr\'echet smooth Banach space, then it contains an isometric copy of every separable Banach space.
A. Szankowski   +11 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Serviteurs devenus maîtres : Focillon et la gravure d’interprétation

open access: yesPerspective, 2019
In the writings of Henri Focillon, engraving is presented like drawings or paintings, in the enclosed world of the artist and his copper plate. The paradox on which this discourse rests is the suppression of the process of replication and diffusion ...
Emmanuel Pernoud
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

La réplique d’expérience en musique : la question de la jouabilité des instruments au musée de la Musique

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art
The replicas of experiments or facsimiles are options that are frequently used in valorising musical heritage. Nonetheless, the notion of musical authenticity is quite complex and reconstructing as best one can an instrument is insufficient to bring a ...
Marie-Anne Loeper-Attia
doaj   +1 more source

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