Results 201 to 210 of about 9,837,393 (260)

Rapid adaptive increase of amylase gene copy number in Indigenous Andeans. [PDF]

Nat Commun
Scheer K, Landau LJB, Jorgensen K, Karageorgiou C, Siao L, Alkan C, Morales Rivera AM, Osborne C, Garcia OA, Pearson L, Kiyamu M, Rivera-Ch M, León-Velarde F, Lee FS, Brutsaert T, Bigham AW, Gokcumen O.   +16 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Oligodendroglial somatic SNCA copy number gains are associated with inclusions and disease onset in multiple system atrophy. [PDF]

Acta Neuropathol
Morley C, Kalef-Ezra E, Perez-Rodriguez D, Jaunmuktane Z, Proukakis C.   +4 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Copy Number Alterations in Canine Urothelial Carcinomas: The Impact of Tumour Purity. [PDF]

Vet Sci
Appenzeller M, Aupperle-Lellbach H, Kehl A, Klopfleisch R, de Brot S.   +4 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Association of Increased MIEN1 Copy Number With Worse Outcomes in Lung Adenocarcinoma and Cervical Cancer. [PDF]

Cureus
Soliman S, Thomas T, Barker V, Aboujaoude M, Angelakakis G, Dabkowski T, Blanck G.   +6 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Plasmid mutation rates scale with copy number. [PDF]

Proc Natl Acad Sci U S A
Ramiro-Martínez P, Quinto I, Jaraba-Soto L, Lanza VF, Herencias-Rodríguez C, González Casanova A, Peña-Miller R, Rodríguez-Beltrán J.   +7 more
europepmc   +1 more source