Results 101 to 110 of about 9,740,536 (302)
Rare copy number variants contribute to congenital left-sided heart disease.
PLoS Genetics, 2012 Left-sided congenital heart disease (CHD) encompasses a spectrum of malformations that range from bicuspid aortic valve to hypoplastic left heart syndrome. It contributes significantly to infant mortality and has serious implications in adult cardiology. Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F R Stewart, Cornelius Boerkoel, Stephen W Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger +27 moredoaj +1 more sourceMetastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano +2 morewiley +1 more sourceA Genome-Wide Investigation of SNPs and CNVs in Schizophrenia [PDF]
, 2009 We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up the top hits in four independent cohorts comprising 1 ...Rujescu, D., Herbert Y Meltzer, Fraser, G., Gennarelli, Massimo, St. Clair, D, JAYATHILAKE K, Rossi Giuseppe, Feng, S, Gennarelli Massimo, Feng, Sheng, Fraser, G, KASPERAVICI, Ge, D., MELTZER HY, Strittmatter, WJ, Fisher, EMC, St Clair, David, RUPPERT A, ROSES AD, Rossi, Giuseppe, Ge Dongliang, Ge, DL, YOON W, NEED AC, David St Clair, RUJESCU D, Sheng Feng, Joseph P McEvoy, Meltzer, Herbert Y, Goldstein, DB, Yoon, Woohyun, St. Clair David, Goldstein, D., Lefkos T Middleton, Meltzer, H., Feng, S., Allen D Roses, Hartmann, Annette M., St Jean, PL, Middleton, Lefkos T., David B Goldstein, Yoon, W, Kasperaviciute, Dalia, Shianna, Kevin V, Moller, HJ, TE D, GOLDSTEIN DB, Kasperavičiūtė, D., Weale, Michael E., Meltzer, HY, FRASER G, Ruppert, A., Middleton, Lefkos T, St Jean, Pamela L, WEALE ME, Shianna, K., Fisher, Elizabeth M. C., Middleton Lefkos T., Heinzen Erin L., Heinzen, E., Crombie Caroline, Ina Giegling, McEvoy, Joseph P, Bonvicini, Cristian, Pamela L St Jean, St. Jean, Pamela L., Keefe, RSE, MÖLLER HJ, Heinzen, EL, Maia, J, Caroline Crombie, Hartmann, A., Need, Anna C, Muglia Pierandrea, Francks, Clyde, St Clair, D, FISHER EM, Dongliang Ge, Giegling Ina, Moeller, H-J, Pierandrea Muglia, Fisher Elizabeth M. C., Goldstein, David B, McEvoy, J., COLA PA, St. Jean Pamela L., Feng Sheng, Cola Philip A., Kasperaviciute, D, Kevin V Shianna, Need Anna C., Weale Michael E., Goldstein, David B., Jessica Maia, Giegling, I., Francks Clyde, Bonvicini, C., Muglia, P., Strittmatter, Warren J., Yoon, W., Ge, Dongliang, McEvoy, JP, Clyde Francks, ROSSI G, Gillian Fraser, Möller, H., Strittmatter, W., MCEVOY JP, St. Clair, D., Ruppert Andreas, Meltzer, Herbert Y., Shianna Kevin V., Fraser, Gillian, Cristian Bonvicini, Roses, Allen D., Gennarelli, M, Warren J Strittmatter, Moeller, Hans-Juergen, Meltzer Herbert Y., Fisher, E., CROMBIE C, Need, AC, Michael E Weale, Ruppert, A, Kasperavičiūtė Dalia, HEINZEN EL, Hartmann, AM, KEEFE RS, Giegling, I, Möller, Hans-Jürgen, Dan Rujescu, Bonvicini Cristian, Goldstein David B., ST CLAIR D, Need, A., Erin L Heinzen, Annette M Hartmann, Heinzen, Erin L, Francks, C, Elizabeth M C Fisher, Gennarelli, M., Muglia, Pierandrea, MIDDLETON LT, Richard S E Keefe, HARTMANN AM, Shianna, KV, Rujescu, Dan, McEvoy Joseph P., Crombie, C., Crombie, Caroline, Strittmatter, Warren J, Woohyun Yoon, Rujescu Dan, St. Jean, P., Ge, D, Karu Jayathilake, McEvoy, Joseph P., Cola, Philip A., Keefe, Richard S E, Jayathilake Karu, Anna C Need, Jayathilake, K., Giegling, Ina, FENG S, Yoon Woohyun, Middleton, LT, Heinzen, Erin L., Roses, Allen D, Cola, PA, Cola, Philip A, St. Clair, David, GE D, Andreas Ruppert, Strittmatter Warren J., Bonvicini, C, St. Jean, PL, Weale, M., Shianna, Kevin V., Cola, P., Rujescu, D, Philip A Cola, Giuseppe Rossi, Middleton, L., Möller Hans-Jürgen, Jayathilake, K, Weale, ME, Jayathilake, Karu, Roses, AD, FRANCKS C, MAIA J, Hartmann, Annette M, Keefe, R., Rossi, G., Roses Allen D., Muglia, P, ST JEAN PL, Roses, A., Fisher, Elizabeth M C, BONVICINI C, Ruppert, Andreas, Maia, Jessica, Massimo Gennarelli, Maia Jessica, GIEGLING I, Francks, C., Keefe Richard S. E., SHIANNA KV, Maia, J., MUGLIA P, Rossi, G, Dalia Kasperaviciūte, Fraser Gillian, Crombie, C, Weale, Michael E, Hartmann Annette M., Need, Anna C., Keefe, Richard S. E., Hans-Jürgen Möller, STRITTMATTER WJ +218 morecore +1 more sourceGenome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]
, 2011 Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...Palmer Cameron D., Schwartz, SM, Benjamin F Voight, Fox, Caroline S., Hwang, Shih-Jen, GIANT Consortium, Launer, Lenore, Hernaez, R, Melissa E. Garcia, Hwang, SJ, Pietiläinen, Kirsi Hannele, Harris, Tamara B, Mitchell, Braxton D., CRISPONI, LAURA, Butler, Johannah L, Massaro, J.M., Gudnason, V., Feitosa, MF, Jeanne M. Clark, Massaro, J., Jørgensen, Torben, O'Donnell Christopher J., Stephen M. Schwartz, Schwartz SM, Palmer, C., Eiriksdottir, Gudny, Joel N Hirschhorn, Kao W. H. Linda, Laura M. Yerges-Armstrong, Stephen M Schwartz, Jeanne M Clark, Borecki Ingrid B., Mitchell, Braxton, Smith, AV, null null, Palmer, C.D., Kao, W.H.L., Johannah L. Butler, Butler, Johannah L., Borecki, IB, Palmer CD, Salomaa, V., Hirschhorn, Joel, Borecki, Ingrid B., Johannah L Butler, Speliotes, Elizabeth K, Fox Caroline S., Shuldiner, Alan R., Fox CS, Hoffmann, Udo, Palmer, CD, Nalls, Michael, Garcia, Melissa E, Hwang SJ, Wu, Jun, Mary F Feitosa, Massaro, Joseph M., Eiriksdottir G, Schadt, EE, Voight, Benjamin F, Nalls, Michael A., Clark, Jeanne M., Eiriksdottir, G, Smith AV, O'Donnell, CJ, Sahani DV, NASH CRN, Schwartz Stephen M., Lauren J Kim, CJ, Butler Johannah L., Speliotes, Elizabeth K., Tamara B Harris, Speliotes, E.K., Feitosa, Mary F., Joseph M. Massaro, Caroline S. Fox, Smith, Albert V, Launer, Lenore J, Shuldiner Alan R., GOLD Consortium, Hoffmann, U, Harris, Tamara, Tamara B. Harris, Garcia Melissa E., Kao, W. H Linda, Albert V. Smith, Mitchell BD, Smith, A.V., Voight, BF, Voight, Benjamin F., Mary F. Feitosa, Alan R Shuldiner, Kim, L.J., Kao, W H Linda, Speliotes EK, Siscovick, DS, Schadt, Eric E., Fox, C.S., Vilmundur Gudnason, Sahani, Dushyant V, Ruben Hernaez, Raychaudhuri, Soumya, Cameron D Palmer, Dushyant V Sahani, Salomaa, Veikko, O'Donnell, Christopher J., Feitosa, Mary, Shuldiner AR, Carr, J Jeffrey, Harris, T.B., Speliotes Elizabeth K., Salomaa, V, Posthuma, D., Tomas, Marta, Palmer, Cameron D, Tomas, M, Wu Jun, Siscovick David S., Launer Lenore J., Palmer, Cameron, et al., de Geus, E.J.C.; id_orcid, Butler, J.L., Clark Jeanne M., Hernaez, R., Mitchell, Braxton D, Borecki, Ingrid B, Shuldiner, A.R., Voight Benjamin F., Benjamin F. Voight, Kao, WH Linda, Lenore J. Launer, Feitosa MF, Siscovick, David, Nalls, M.A., Carr, J. Jeffrey, Clark, JM, Garcia, Melissa E., Lenore J Launer, Hirschhorn Joel N., Hwang, S.J., Eiriksdottir, G., Launer, L.J., Laura M Yerges-Armstrong, Melissa E Garcia, Hwang, S., Christopher J O'Donnell, Yerges-Armstrong, Laura M., Clark, J., Kim Lauren J., Launer, Lenore J., Hirschhorn JN, Harris, Tamara B., Michael A. Nalls, Launer LJ, Boomsma, D.I.; id_orcid, J Jeffrey Carr, Massaro, JM, Braxton D. Mitchell, Posthuma, D.; id_orcid, Heijer, M. den, Shih-Jen Hwang, Siscovick, David S., Mitchell, BD, Siscovick DS, Gudnason V, Yerges-Armstrong, L.M., Launer, LJ (Lenore), Gudnason, Vilmundur, Veikko Salomaa, de Geus, E.J.C., O' DONNELL, Willemsen, G.; id_orcid, Mitchell, B., Shuldiner, Alan, Kim, Lauren J, Sahani Dushyant V., Smith Albert V., David S Siscovick, Schadt, Eric, Kao WH, Fox, CS, David S. Siscovick, Carr JJ, Butler, Johannah, Massaro, Joseph, Hoffmann U, Garcia, Melissa, Tomas Marta, Mitchell Braxton D., Christopher J. O'Donnell, Lokki, Marja-Liisa, Gudnason Vilmundur, Fox, Caroline, DIAGRAM Consortium, Schadt, E.E., Tomas M, Hirschhorn, J.N., Jun Wu, Nalls, M., Ingrid B Borecki, Launer, L., Harris TB, Palmer, Cameron D., O'Donnell, C.J., Nalls MA, Voight BF, Borecki IB, Salomaa V, Massaro, Joseph M, Voight, B.F., Nalls, MA, O'Donnell, Christopher J, Garcia, M., Harris Tamara B., Kao, W., Kao, WH, Elizabeth K Speliotes, Gudnason, V, Siscovick, D.S., Yerges-Armstrong, Laura, Siscovick, David S, Cameron D. Palmer, Smith, Albert, Garcia ME, Marta Tomas, Clark, Jeanne M, Eric E. Schadt, Hottenga, J.J., Wu, J, Caroline S Fox, Joel N. Hirschhorn, Wu, J., Hoffmann Udo, Schadt EE, Albert V Smith, Carr J. Jeffrey, Sahani, D.V., J. Jeffrey Carr, Michael A Nalls, Feitosa, Mary F, Kao, W.H., O'Donnell, Christopher, Kim LJ, Nalls Michael A., Feitosa Mary F., Schwartz, S.M., Smith, Albert V., Shuldiner, Alan R, Voight, Benjamin, Wu J, Alan R. Shuldiner, Borecki, Ingrid, Massaro Joseph M., Lauren J. Kim, Schwartz, Stephen M, SCUTERI, ANGELO, Kao, WHL, Speliotes, Elizabeth, Kim, LJ, Clark, Jeanne, Carr, J.J., Nalls, Michael A, Feitosa, M.F., Harris, TB, Willemsen, G., Hirschhorn, Joel N., Clark JM, Yerges-Armstrong, L., Ingrid B. Borecki, Eric E Schadt, Butler, J., Butler JL, Schwartz, Stephen, Yerges-Armstrong LM, Garcia, M.E., Hernaez Ruben, Shuldiner, AR, GIANT, Boomsma, D.I., Kim, L., Elizabeth K. Speliotes, O’Donnell, C., Clark, J.M., Yerges-Armstrong, Laura M, Kim, Lauren J., Garcia, ME, Joseph M Massaro, Mitchell, B.D., Massaro JM, Speliotes, EK, Kim, Lauren, Udo Hoffmann, Jansson, John-Olov,, W H Linda Kao, MAGIC Investigators, Launer, LJ, Shuldiner, A., Hirschhorn, Joel N, Salomaa Veikko, Dushyant V. Sahani, Hwang Shih-Jen, Tomas, M., Hernaez R, Geus, E.J.C. de, Borecki, I.B., Kao, W. H. Linda, Hwang, Shih Jen, Butler, JL, Sahani, Dushyant, Hirschhorn, JN, Sahani, Dushyant V., Speliotes, E., YERGES ARMSTRONG LM, Yerges-Armstrong Laura M., Hernaez, Ruben, Eiriksdottir Gudny, Sahani, DV, Gudny Eiriksdottir, Braxton D Mitchell, Schadt Eric E., Schadt, Eric E, Hoffmann, U., PAOLISSO, Giuseppe, Schwartz, Stephen M., W. H. Linda Kao, Carr, JJ, Yerges-Armstrong, LM, Fox, Caroline S, Kaplan, Robert C., Chalasani, Naga, Welch, Ryan, Assimes, Themistocles L., Sanna, Serena, Teslovich, Tanya M., Hengstenberg, Christian, Zgaga, Lina, Dasarathy, Srinivasan, Peters, Annette, Gyurkey, Grace, Kaprio, Jaakko, Ketkar, Shamika, Navarro, Pau, Qi, Lu, Monda, Keri L., Gejman, Pablo V., Lawrence, Robert W., Abecasis, Gonçalo R., Diehl, Anna Mae, White, Melanie, Valle, Timo T., Facheris, Maurizio F., Frayling, Timothy M., Jarvelin, Marjo-Riitta, Liu, Jianjun, Piercy, Dawn, Ludwig, Barbara, Wang, Chia, Killenberg, Paul, Kilpeläinen, Tuomas O., Almgren, Peter, Balmforth, Anthony J., Huikuri, Heikki V., Gräβler, Jürgen, Strachan, David P., Waeber, Gérard, Bergman, Richard N., König, Inke R., Ingelsson, Erik, Workalemahu, Tsegaselassie, Lajunen, Taina, Kwan, Samantha, Nelson, James, Gloyn, Anna L., Clark, Lisa, Lehtimäki, Terho, Vitart, Veronique, Iribarren, Carlos, Stringham, Heather M., Chasman, Daniel I., Weedon, Michael N., Selph, Kimberly, Mc, Steven A., Contos, Melissa J., Farooqi, I. Sadaf, Erdmann, Jeanette, O'Rahilly, Stephen, Loos, Ruth J. F., Roberts, Sarah, Hall, Per, Rafelt, Suzanne, Hicks, Andrew A., Munroe, Patricia B., Dupuis, Josée, Mägi, Reedik, Quertermous, Thomas, Gaget, Stefan, Gyllensten, Ulf, Dehghan, Abbas, Manunta, Paolo, Perola, Markus, Wallaschofski, Henri, Heard-Costa, Nancy L., Ruokonen, Aimo, Sargeant, Carol, Molleston, Jean, King, Debra, Polasek, Ozren, Koskinen, Seppo, Ziegler, Andreas, Dixon, Anna L., van Duijn, Cornelia M., Bass, Nathan M., Smith, Melissa, Klipsch, Ann, Raitakari, Olli, Randall, Joshua, Zhang, Qunyuan, Wilson, James F., Wiegand, Susanna, Bhimalli, Prajakta, Robertson, Neil R., Schlessinger, David, Illig, Thomas, Hoesel, Volker, Rogers, Nicholette, Ruth Sargent, P. A. -C., Myers, Richard H., Laakso, Markku, Hayes, Richard B., Knowles, Joshua W., Buchanan, Thomas A., Visscher, Peter M., Lamina, Claudia, Chen, Chih-Mei, Ngwa, Julius S., Wheeler, Eleanor, Lanzani, Chiara, Duan, Jubao, Purcell, Shaun, Luan, Jian'an, Edwards, Kevin, Elosua, Roberto, Caulfield, Mark J., Kleiner, David, Jeffrey Carr, J., Ebrahim, Shah, Greenawalt, Danielle M., Sandhu, Manjinder S., Guiducci, Candace, Yeh, Matthew, Smit, Jan H., Bragi Walters, G., MAGIC Investigators, ,, Hall, Alistair S., Berndt, Sonja I., Kvaløy, Kirsti, Campbell, Harry, Narisu, Narisu, Folsom, Aaron R., Rayner, Nigel W., Schwimmer, Jeffrey B., Watanabe, Richard M., Allen, Hana Lango, Graham, Martin, Day, Ian N. M., Hu, Frank B., Atwood, Larry D., Mooney, Jody, Mulic, Rosanda, Groop, Leif C., Tammesoo, Mari-Liis, Brancati, Fred, Chanock, Stephen J., Franklin, Christopher S, Jacobs, Kevin B., Colvin, Ryan, Grönberg, Henrik, Peltonen, Leena, Widen, Elisabeth, Boehnke, Michael, Thomson, Brian, Brunt, Elizabeth, Johansson, Åsa, Green, Mika, Preuss, Michael, Witte, Daniel R., Steinthorsdottir, Valgerdur, Pichler, Irene, Silander, Kaisa, Xu, Jianfeng, Zitting, Paavo, Spector, Timothy D., Egan, Josephine M, Wilson, Laura, Khaw, Kay-Tee, Lecoeur, Cecile, Platou, Carl G. P., Stefansson, Kari, Cappuccio, Francesco P., Boomsma, Dorret I., Marek, Diana, Kovacs, Peter, Tönjes, Anke, Chatterjee, Nilanjan, Jones, Amy, Rissanen, Aila, Kraft, Peter, Stager, Margaret, Soranzo, Nicole, Hayward, Caroline, Schwarz, Peter, Igl, Wilmar, Filipowski, Danuta, Gustafsson, Stefan, Gieger, Christian, Viikari, Jorma, Hinney, Anke, NASH CRN, ,, Van Natta, Mark, Barlow, Sarah, Tyrer, Jonathan P., Hottenga, Jouke Jan, Kuusisto, Johanna, Thorleifsson, Gudmar, Neville, Matt J., Watkins, Hugh, Arnold, Alice M., Paré, Guillaume, Scott, Laura J., Oostra, Ben, Pellikka, Niina, Aspelund, Thor, van Meurs, Joyce B. J., Gottfried, Marcia, Boes, Tanja, Song, Kijoung, Petcharaporn, Lita, Schunkert, Heribert, Kathiresan, Sekar, Jula, Antti, Froguel, Philippe, Belt, Patricia, Wild, Sarah H., Lavine, Joel E., Uitterlinden, André G., Jansson, John-Olov, Sanyal, Arun J., Ripatti, Samuli, Connell, John, Yates, Katherine, Ridker, Paul M., Tuomilehto, Jaakko, Ouwehand, Willem H., Jewell, Elizabeth, Lantieri, Olivier, McKnight, Barbara, Pedersen, Oluf, Goddard, Michael E., Amin, Najaf, Linda Kao, W. H., Kettunen, Johannes, Rosenthal, Philip, Jackson, Anne U., Elliott, Paul, Vogel, Carla I. G., Isaacson, Milana, den Heijer, Martin, Hoofnagle, Jay H., Lanzani C, Boerwinkle, Eric, Wabitsch, Martin, Heinrich, Joachim, Vedantam, Sailaja, Perry, John R. B., Fischer-Posovszky, Pamela, Stewart, Susan, Rzehak, Peter, Wood, Andrew R., Lettre, Guillaume, Friedrich, Nele, Hartikainen, Anna-Liisa, Lee, Lydia, Surakka, Ida, Goel, Anuj, Erdos, Michael R., Shi, Jianxin, Behling, Cynthia, Havulinna, Aki S., Freimer, Nelson B., Hebebrand, Johannes, ?, ?, Zhao, Jing Hua, Yang, Jian, Winkler, Thomas W., Kaplan, Lee M., Kiemeney, Lambertus A., Kajantie, Eero, Donithan, Michele, Uda, Manuela, Isomaa, Bo, Prokopenko, Inga, Parker, Alex N., Bergmann, Sven, Groves, Christopher J., Lawlor, Debbie A., Cavalcanti-Proença, Christine, Steel, Tessa, Sparsø, Thomas, Bringman, Diane, Henneman, Peter, Visvikis-Siest, Sophie, Liu, Yao-Chang, Thompson, John R., Savolainen, Markku J., Ridderstråle, Martin, McArdle, Wendy L., Scherag, Susann, McCullough, Arthur, Pan, Yi-Ping, Grarup, Niels, Aben, Katja K., Adrienne Cupples, L., Chen, Yii-Der Ida, Ferreira, Teresa, Busonero, Fabio, Miriel, Laura, Park, Ju-Hyun, Stead, Alice, Haritunians, Talin, Bryan, Daphne, Penninx, Brenda W., Wright, Alan F., Thiering, Elisabeth, Tardif, Jean-Claude, Morris, Andrew P., Coin, Lachlan J. M., Ong, Ken K., Fuchs, Michael, Sinisalo, Juha, Homuth, Georg, Deloukas, Panos, Jarick, Ivonne, Wiklund, Fredrik, Wareham, Nicholas J., Laitinen, Jaana, Hawkins, Carol, Brown, Morris J., Stumvoll, Michael, Karpe, Fredrik, Timpson, Nicholas J., Pietiläinen, Kirsi H., Hofman, Albert, Durelle, Janis, Glazer, Nicole L., Meitinger, Thomas, Li, Shengxu, Neuschwander-Tetri, Brent A., Luben, Robert N., Bornstein, Stefan R., Moffatt, Miriam F., Vuppalanchi, Raj, Krude, Heiko, Robuck, Patricia R., McCarthy, Anne, Sandhu, Bimalijit, Wichmann, H. -Erich, Sternberg, Alice, Stein, Tanya, Guy, Cynthia, Hassanein, Tarek, Bambha, Kiran, Doney, Alex, Hveem, Kristian, Mohlke, Karen L., Midthjell, Kristian, Heid, Iris M., Lindgren, Cecilia M., Kutalik, Zoltán, Hattersley, Andrew T., Abdelmalek, Manal, Sirlin, Claude, Kaakinen, Marika, Martin, Nicholas G., Samani, Nilesh J., Bouatia-Naji, Nabila, Alavere, Helene, Langenberg, Claudia, Barroso, Inês, Siegner, Joan, Eriksson, Johan G., Doo, Edward, Carola Zillikens, M., Geus, Eco J. C., North, Kari E., Biebermann, Heike, Teder-Laving, Maris, Ragozzino, Linda, Swift, Amy, Pouta, Anneli, Lorentzon, Mattias, Sanders, Alan R., Schreiber, Stefan, Rivadeneira, Fernando, Derdoy, Jose, Grallert, Harald, Willemsen, Gonneke, Saramies, Jouko, Vatin, Vincent, Fu, Mao, Clarke, Robert, Rosenthal, Monique, Luketic, Velimir A. C., Mangino, Massimo, Tonascia, James, Barlassina, Christina, Ünalp, Aynur, Thorsteinsdottir, Unnur, Willer, Cristen J., Macciardi, Fabio, Hassanali, Neelam, Cummings, Oscar W., Stephens, Jonathan, Chines, Peter, John, Ulrich, Meyre, David, McCarthy, Mark I., Saxena, Richa, Hunter, David J., Marre, Michel, Merriman, Raphael, Navarro, Pau; id_orcid, Boeing, Heiner, O'DONNELL CJ, Jousilahti, Pekka, Kowdley, Kris V., Fisher, Eva, Rudan, Igor, Felix, Stephan B., Sandholt, Camilla, Reinehr, Thomas, Beckmann, Jacques S., Smith, George Davey, Morken, Mario A., van Ommen, Gert-Jan, Nelis, Mari, Ben-Shlomo, Yoav, White, Charles C., Alibrandi, Maria T. S., Everhart, Jay, Esko, Tõnu, Cooper, Matthew N., Absher, Devin M., Estrada, Karol, Johnson, Toby, Rief, Winfried, Gjesing, Anette P., GIANT Consortium, ,, MANUNTA P, Saunders, Cheryl, Scherag, Andre, Bennett, Amanda J., Hoffmann, Joyce, Nemesh, James, Kim, Wana, Heath, Andrew C., van Wingerden, Sophie, Blakemore, Alexandra I. F., Hui, Jennie, Pabst, Mark, Gold Consortium, ,, Montgomery, Grant W., Goyette, Philippe, Ferrell, Linda D., Levinson, Douglas F., Thompson, Judy, Bonnycastle, Lori L., Balkau, Beverley, Melander, Olle, Liang, Liming, Kolcic, Ivana, Segrè, Ayellet V., Seeff, Leonard, Kinnunen, Leena, Rybin, Denis, Nieminen, Markku S., Hansen, Torben, Sovio, Ulla, Witteman, Jacqueline C., Waite, Lindsay L., Nyholt, Dale R., Beilby, John P., Schipf, Sabine, Peters, Marjolein J., James, Alan L., O'Connell, Jeffrey R., Weyant, Robert J., Boyett, Sherry, Pramstaller, Peter P., Ohlsson, Claes, Kähönen, Mika, Tuomi, Tiinamaija, Metspalu, Andres +803 morecore +5 more sourcesEXCAVATOR: detecting copy number variants from whole-??exome sequencing data [PDF]
, 2013 We developed a novel software tool, EXCAVATOR, for the detection of copy number variants (CNVs) from whole-exome sequencing data. EXCAVATOR combines a three-step normalization procedure with a novel heterogeneous hidden Markov model algorithm and a ...B. Giusti, D\u27Aurizio, Romina, Cristina Battaglia, Tattini, Lorenzo, E. Bonora, Magi, Alberto, Gensini, Gian Franco, Abbate, Rosanna, A. Magi, R. Abbate, Pamela Magini, G. Bellis, Gian Franco Gensini, Pippucci, Tommaso, A. Kurg, Magini, Pamela, Alberto Magi, Elena Bonora, G. Gensini, Benelli, M., Matteo Benelli, Ingrid Cifola, Battaglia, Cristina, M. Seri, Romina D’Aurizio, T. Pippucci, Mangano, Eleonora, De Bellis, Gianluca, Benelli, Matteo, M. Benelli, Ants Kurg, C. Battaglia, L. Tattini, R. D'Aurizio, Kurg, Ants, Betti Giusti, Lorenzo Tattini, P. Magini, Seri, Marco, Bonora, Elena, Giovanni Romeo, G. Romeo, Rosanna Abbate, Eleonora Mangano, Giusti, Betti, I. Cifola, Cifola, Ingrid, Gianluca De Bellis, Marco Seri, Tommaso Pippucci, Romeo, Giovanni, E. Mangano +51 morecore +2 more sourcesThe role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti +11 morewiley +1 more source
