Results 151 to 160 of about 254,836 (309)

Germline copy number variations associated with breast cancer susceptibility in a Japanese population [PDF]

, 2012
Yutaka Suehiro, Takae Okada, Naoya Shikamoto, Yibo Zhan, Kohei Sakai, Naoko Okayama, M. Nishioka, Tomoko Furuya, Atsunori Oga, Shigeto Kawauchi, Noriko Maeda, Michiko Tamesa, Yukiko Nagashima, Shigeru Yamamoto, Masaaki Oka, Yuji Hinoda, Kohsuke Sasaki   +16 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Optimizing Liquid Biopsy: Spike-In Panel Approach for ctDNA Copy Number Variation Analysis. [PDF]

Cancer Genomics Proteomics
Kim H, Kim BM, Kim J, Seo SH, Hwang SM, Park KU.   +5 more
europepmc   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Dosage effect of copy number variation in epilepsy and ten regions of the human brain. [PDF]

Sci Rep
De T, Coin L, Johnson MR.
europepmc   +1 more source

Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia [PDF]

, 2006
Ilan Braude, Bisera Vukovic, Mona Prasad, Paula Marrano, Stefanie Turley, Dwayne L. Barber, Maria Zieleńska, Jeremy A. Squire   +7 more
openalex   +1 more source

Copy number variation doesn't copy SNPs [PDF]

Nature Reviews Genetics, 2007
openaire   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice. [PDF]

Front Genome Ed
Park H, Kuroha T, Saika H, Kuroda M, Yoshida H.   +4 more
europepmc   +1 more source