Results 171 to 180 of about 182,078 (261)

Correction to: Enhancing interpretation of clinical disease-associated copy number variations from multiple sequencing strategies with CNVSeeker. [PDF]

Bioinformatics
europepmc   +1 more source

Tool Comparison for Detecting Tumour Cells in Endometrial Cancer via Single-Cell Copy Number Variations Analysis. [PDF]

J Cell Mol Med
Dugo E, Piva F, Giulietti M, Giannella L, Ciavattini A.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Abundant β-Defensin Copy Number Variations in Pigs. [PDF]

Genes (Basel)
Kim D, Cho HS, Kang M, Ahn B, Shin J, Park C.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

ZIPcnv: accurate and efficient inference of copy number variations from shallow whole-genome sequencing. [PDF]

Bioinformatics
Xue Z, Zeng J, Wang X, Yuan J, Wang T, Lai X, Wang L, Wang Y, Zhu H, Jin X, Wang J.   +10 more
europepmc   +1 more source

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

Identification of copy number variations through whole genome resequencing between Jiuyishan and Hyplus rabbits. [PDF]

Front Vet Sci
Wang Y, Wang J, Ding H, Yang L, Zhao H, Huang D.   +5 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Combining pangenomics and population genetics finds chromosomal re-arrangements, diversified chromosome segments, copy number variations and transposon polymorphisms in wheat and rye powdery mildew. [PDF]

PLoS Pathog
Sotiropoulos AG, Müller MC, Kunz L, Graf JP, Kiss L, Hückelhoven R, Schlagenhauf E, Keller B, Wicker T.   +8 more
europepmc   +1 more source