Results 231 to 240 of about 182,078 (261)
Some of the next articles are maybe not open access.
Copy number variation in the cattle genome
Functional & Integrative Genomics, 2012Copy number variations (CNVs) are gains and losses of genomic sequence greater than 50 bp between two individuals of a species. While single nucleotide polymorphisms (SNPs) are more frequent, CNVs impact a higher percentage of genomic sequence and have potentially greater effects, including the changing of gene structure and dosage, altering gene ...
George E, Liu, Derek M, Bickhart
openaire +2 more sources
Gene copy number variation in schizophrenia
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2007AbstractRecent reports have highlighted the possibility that gene copy number variations play a role in the development of complex disorders and have suggested that some variations are very common in schizophrenic patients. We have carried out a comparative genomic hybridization screen using oligonucleotide probes of 891 candidate genes to look for ...
Smitha R, Sutrala +3 more
openaire +2 more sources
Copy number variation in the autism genome
Expert Opinion on Medical Diagnostics, 2008Autism spectrum disorders (ASDs) are among the most heritable of all neurodevelopmental disorders. Despite intense research there has been limited success in deciphering the etiology of ASDs.It has been shown that chromosomal rearrangements play an important role in ASDs.
openaire +2 more sources
The role of copy number variation in schizophrenia
Expert Review of Neurotherapeutics, 2010Recent developments in microarray technology have revealed the presence of many submicroscopic deletions and duplications in the human genome. Some of these have been found to increase the risk for neuropsychiatric disorders. Over the last 2 years, several large studies on schizophrenia have implicated large deletions and duplications that increase the
openaire +2 more sources