Results 101 to 110 of about 2,835,414 (282)

Cor ad Cor Loquitur: John Henry Newman y la Amistad [PDF]

, 2020
J. H. Newman is known as a convert, an educator and a theologian, however, the twenty thousand letters he wrote testify to another aspect of his personality: A good friend.
Corona, Marial
core  

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

A qualitative chemometric study of resin composite polymerization [PDF]

RGO: Revista Gaúcha de Odontologia, 2008
Objective: An experiment was carried out to assess the effect produced by different polymerization techniques on resin composite color after it has been immersed in coffee. Methods: Samples were manufactured using TPH Spectrum composite.
Regina Ferraz Mendes, José Machado Moita Neto, Raimundo Rosendo Prado Junior, Daniela Moura Parente   +3 more
doaj  

COR BILOCULARE [PDF]

Heart, 1952
M, CAMPBELL, F, GARDNER, G, REYNOLDS
openaire   +2 more sources

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Aspecten van geweldpleging naar voorschriften van de Nederlandse staatsorganisatie [PDF]

, 1973
Tot de belangrijkste onderwerpen van het vak 'strafrecht', zoals dat aan de juridische faculteit van de Erasmus Universiteit Rotterdam – evenals trouwens aan die van de andere instellingen van wetenschappelijk onderwijs in Nederland, v.z.v.
Gutter, C. (Cor)
core  

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Dermatoscopia del angiomixoma superficial

Actas Dermo-Sifiliográficas, 2021
E. Amores-Martín, M. de los Ángeles Sola Casas, M.T. Fernández-Figueras   +2 more
doaj   +1 more source

Cor umbilical? [PDF]

, 2007
Un estudi mostra que les cèl·lules mare derivades de sang de cordó umbilical mostren trets de cèl·lula muscular cardíaca. Aquest estudi, i el fet que la recollida de sang de cordó després del naixement s'ha convertit en pràctica habitual, obren grans ...
Bayés-Genís, Antoni
core   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source