Results 141 to 150 of about 1,042,655 (286)

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang   +5 more
wiley   +1 more source

Enhanced 2D Spiral Cine DENSE MRI Using Low‐Rank Denoising for Improved Apparent Signal‐to‐Noise Ratio, Spatial Resolution, Efficiency, Accuracy, and Accessibility

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a denoising technique for displacement encoding with stimulated echoes (DENSE) MRI that improves spatial resolution, efficiency, and accuracy, and enhances accessibility by implementing DENSE MRI at 0.55 T. Methods We developed a low‐rank denoising technique, which leverages multidimensional spiral cine DENSE MRI data for ...
Shu‐Fu Shih   +9 more
wiley   +1 more source

Asynchrony Related to Mechanical Ventilation Exacerbates Diaphragm Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims In dystrophic mice (mdx, a genetic homolog of Duchenne muscular dystrophy: DMD), previous studies showed that mechanical ventilation (MV) induces ventilator‐induced diaphragmatic dysfunction (VIDD). However, susceptibility to mechanical stress caused by asynchrony remains unknown.
Mohamad Yehya   +7 more
wiley   +1 more source

Workplace Incivility and Nurses' Health: The Mediating Role of Positive and Negative Affect

open access: yesResearch in Nursing &Health, EarlyView.
ABSTRACT Nurses are particularly vulnerable to workplace incivility, a form of deviant behavior that can evolve into severe workplace mistreatment. Although the psychological and organizational consequences of incivility have been documented, its impact on health, particularly through emotional pathways, remains unclear.
Ju Yeon Lee   +4 more
wiley   +1 more source

Proteomic Characterization of AS1411 Reveals ATP6AP1 as a Mediator of Triple‐Negative Breast Cancer Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae   +6 more
wiley   +1 more source

Made in the shade: Leaf responses of native wildflowers to single‐axis photovoltaic solar energy

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
As solar energy expands globally, balancing renewable power generation with biodiversity and ecosystem health has become an urgent challenge. This study investigated how native wildflowers respond at leaf level to the unique microclimates created by rotating solar panels in California's Central Valley.
Yudi Li   +3 more
wiley   +1 more source

Open‐land‐derived agroforestry and effects of abandonment of management of the main crop on ecosystem services and woody plant diversity

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Tropical forests are rapidly declining. One promising strategy to reverse the loss of tropical forest is the establishment of agroforestry on open land. We combined interviews with biodiversity surveys to learn general lessons from success and nonsuccess stories of the establishment of open‐land‐derived coffee agroforests in one of the world's ...
Lucas M. Fonzaghi   +3 more
wiley   +1 more source

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