Results 51 to 60 of about 120,789 (248)

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

open access: yesAdvanced Science, EarlyView.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing   +7 more
wiley   +1 more source

Non‐Native Herpetofauna Continue to Proliferate in the World's Most Invaded Herpetofauna Community

open access: yesEcology and Evolution
The spread of non‐native species continues to increase around the globe, highlighting the importance of understanding both the dynamics of the invaded communities in which non‐natives comprise a high percentage of the total fauna and the factors that may
Stephanie L. Clements   +5 more
doaj   +1 more source

Devices, Functions, and Applications of Artificial Neuromorphic Visual Systems

open access: yesAdvanced Science, EarlyView.
This review highlights recent advances in optoelectronic synapses for artificial neuromorphic vision, emphasizing their material systems, structural designs, and performance metrics. It further discusses visual neural networks enabled by these synapses, covering perception, memory, and recognition functionalities, and analyzes challenges in stability ...
Jiaxin Liu   +4 more
wiley   +1 more source

De Novo Design of High‐Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor

open access: yesAngewandte Chemie, EarlyView.
Hybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gizem Gokce‐Alpkilic   +18 more
wiley   +2 more sources

Mapping global coral vulnerability to stony coral tissue loss disease: implications for biosecurity and conservation

open access: yesFrontiers in Marine Science
Stony Coral Tissue Loss Disease (SCTLD) has devastated Caribbean coral reefs since 2014, but its potential for global impact remains uncertain. We developed predictive models to assess the worldwide vulnerability of coral reefs to SCTLD under different ...
Kevin D. Lafferty, Giovanni Strona
doaj   +1 more source

Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models

open access: yesAdvanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant   +28 more
wiley   +1 more source

SERS‐AI‐LUA‐Driven Salivary Diagnosis of Head and Neck Cancer Using Graphene‐Assisted Plasmonic Nanocorals

open access: yesAdvanced Science, EarlyView.
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo   +11 more
wiley   +1 more source

A scanning particle image velocimetry system for spatial mapping of steady flow and O2 concentration fields around aquatic organisms

open access: yesMethods in Ecology and Evolution
The impact of flow on aquatic organisms (and vice versa) is crucial for many aspects of their physiology and ecology, as this interaction shapes the hydrodynamic boundary layer and thereby the exchange of solutes between the organism and its surrounding ...
Cesar O. Pacherres   +3 more
doaj   +1 more source

The hoax of ocean acidification

open access: yesQuaestiones Geographicae, 2019
A widespread alarm is sweeping the world at present about the ill effects of man-made increases in carbon dioxide (CO2) production. One aspect is that it may cause the ocean to become acid, and dissolve the carbonate skeletons of many living things ...
Ollier Clifford
doaj   +1 more source

Home - About - Disclaimer - Privacy