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Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page 210-223, February 2026.
Optimal treatment for frontal fibrosing alopecia (FFA) remains contentious. An international expert panel agreed that highly/ultra‐potent topical steroids were the preferred first‐line topical therapy. Preferred systemic therapies were 5‐alpha reductase inhibitors, followed by hydroxychloroquine.
Nekma Meah, Jane Li, Dmitri Wall, Katherine York, Bevin Bhoyrul, Laita Bokhari, Lachlan Coulthard, Leila Asfour, Leonardo Spagnol Abraham, Daniel Asz‐Sigall, Wilma F. Bergfeld, Regina C. Betz, Ulrike Blume‐Peytavi, Valerie Callender, Vijaya Chitreddy, Andrea Combalia, George Cotsarelis, Brittany Craiglow, Rachita Dhurat, Ncoza Dlova, Jeff Donovan, Andrei Doroshkevich, Samantha Eisman, Paul Farrant, Aida Gadzhigoroeva, Jack Green, Ramon Grimalt, Matthew Harries, Maria Hordinsky, Alan D. Irvine, Victoria Jolliffe, Spartak Kaiumov, Brett King, Steven Kossard, Joyce Lee, Won‐Soo Lee, Nino Lortkipanidze, Amy McMichael, Natasha Atanaskova Mesinkovska, Andrew Messenger, Paradi Mirmirani, Elise Olsen, Seth J. Orlow, Yuliya Ovcharenko, Bianca Maria Piraccini, Rodrigo Pirmez, Adriana Rakowska, Pascal Reygagne, Janet Roberts, Lidia Rudnicka, David Saceda‐Corralo, Jerry Shapiro, Pooja Sharma, Tatiana Silyuk, Poonkiat Suchonwanit, Anita Takwale, Antonella Tosti, W. I. Visser, Sergio Vañó‐Galván, Annika Vogt, Martin Wade, Leona Yip, Abraham Zlotogorski, Cheng Zhou, Rodney Sinclair   +64 more
wiley   +1 more source

Acute Heat Priming Dampens Gene Expression Response to Thermal Stress in a Widespread <i>Acropora</i> Coral. [PDF]

Ecol Evol
Stick DJA, Kennington WJ, Castro-Sanguino C, Duffy SL, Gilmour JP, Thomas L.   +5 more
europepmc   +1 more source

Coral cover and species responses to heat exposure vary across contemporary Western Atlantic reefs. [PDF]

Sci Rep
Webb AE, Perry CT, González-Barrios FJ, Morris JT, van Hooidonk R, Smith TB, French DR, Johnston MA, Garcia R, Rodriguez MV, Ruzicka RR, Colella MA, Enochs IC.   +12 more
europepmc   +1 more source

Diagnosis of gallbladder villous tubular adenoma with high-grade intraepithelial neoplasia via peroral endoscopic choledochoscopy: a rare case of an elderly patient. [PDF]

Endoscopy
Zhang J.
europepmc   +1 more source

Marine nutraceuticals as a source of SIRT1 and NRF2 activators for diabetes and aging-related metabolic disorders. [PDF]

Diabetol Metab Syndr
Hadinata E, Harbuwono DS, Soegondo S, Prajitno JH, Mudjanarko SW, Taslim NA, Hasyyati EY, Frediansyah A, Surya R, Cahyono MBA, Santini A, Tjandrawinata RR, Romano R, De Luca L, Nurkolis F.   +14 more
europepmc   +1 more source

AKG-TET axis is central to senescence plasticity. [PDF]

iScience
Akakura S, Tabibzadeh S.
europepmc   +1 more source

An Atypical Presentation of Sporadic Creutzfeldt-Jakob Disease in the Setting of Chronic Alcohol Use Disorder. [PDF]

Case Rep Neurol Med
Holt C, Sadek AT, Woodard J, Grinstead R.   +3 more
europepmc   +1 more source

Call to action: climate change and health threats to the Pacific Islands. [PDF]

Trop Med Health
Damore SM, Ferguson Irlanda CE, Barry M.
europepmc   +1 more source

Complete genome sequencing of 18 urea-utilizing Vibrio strains isolated from coral. [PDF]

Sci Data
Li K, Lin W, Zhou J, Liu C, Syaifudin M, Huang J, Pei P, Du H, Li T.   +8 more
europepmc   +1 more source

High microbial diversity, functional redundancy, and prophage enrichment support the success of the yellow pencil coral, <i>Madracis mirabilis,</i> in Curaçao's coral reefs. [PDF]

mSystems
Wallace BA, Varona NS, Stiffler AK, Vermeij MJA, Silveira C.   +4 more
europepmc   +1 more source