Results 141 to 150 of about 1,931,209 (398)

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

Neurophysiological markers predicting recovery of standing in humans with chronic motor complete spinal cord injury

open access: yesScientific Reports, 2019
The appropriate selection of individual-specific spinal cord epidural stimulation (scES) parameters is crucial to re-enable independent standing with self-assistance for balance in individuals with chronic, motor complete spinal cord injury, which is a ...
Samineh Mesbah   +5 more
doaj   +1 more source

Headphone with in-axle cord connector [PDF]

open access: yes, 2015
A headset including a headband having two end portions each coupled to a respective speaker housing. One or both of the end portions includes a cord connector or jack wherein an audio cord may be coupled. The cord connector is arranged on the headband in
Blonder, Greg
core  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Global prevalence and incidence of traumatic spinal cord injury

open access: yesClinical Epidemiology, 2014
Background Spinal cord injury (SCI) is a traumatic event that impacts a patient’s physical, psychological, and social well-being and places substantial financial burden on health care systems.
Anoushka Singh   +4 more
semanticscholar   +1 more source

Direct Ink Writing of Conductive Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho   +6 more
wiley   +1 more source

Minimum toe clearance: probing the neural control of locomotion

open access: yesScientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen   +8 more
doaj   +1 more source

A functional exchange shunt in the umbilical cord: the role of coiling in solute and heat transfer [PDF]

open access: yesarXiv
The umbilical cord plays a critical role in delivering nutrients and oxygen from the placenta to the fetus through the umbilical vein, while the two umbilical arteries carry deoxygenated blood with waste products back to the placenta. Although solute exchange in the placenta has been extensively studied, exchange within the cord tissue has not been ...
arxiv  

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