Results 191 to 200 of about 1,618,018 (347)

A Canine Musculoskeletal Robot for Investigating Biomechanical Functions During Locomotion

Advanced Robotics Research, EarlyView.
In this study, a dog limb musculoskeletal robot was developed using thin McKibben artificial muscles to investigate the effects of the dog's musculoskeletal structure on walking. Walking experiments were conducted in both indoor and outdoor environments, suggesting that the flexible structure of the dog's shoulders contributes to an increase in stroke ...
Hana Ito, Shoma Tanaka, Yunhao Feng, Hiroyuki Nabae, Yasuji Harada, Akira Fukuhara, Koichi Suzumori   +6 more
wiley   +1 more source

COVID‐19 and Its Impact on Collection and Processing of Cord Blood Units at the Cleveland Cord Blood Center

Stem Cells Translational Medicine, 2020
Kathy Bobik‐Kurz, Marcie Finney, Kim Vincent, Mary Laughlin   +3 more
doaj   +1 more source

Variations in Managing Acute Spinal Cord Injury in the North American Clinical Trials Network and Partner Institutes. [PDF]

Global Spine J
Gebeyehu TF, Sokol Z, Guest JD, Harrington JD, Kabani AS, Fitchett E, Lopez A, Matsoukas S, Franco D, Jallo J, Vaccaro AR, Abd-El-Bar M, Kurpad SN, Tator CH, Fehlings MG, Harrop J.   +15 more
europepmc   +1 more source

Intramedullary spinal cord hemangioma: A rare case report

, 2023
Tam Truong Faulds, Vanessa Milan, Soheil Sharifi-Amina, Charles Stout, Duy Bui   +4 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Intraoperative Ultrasound Imaging Features Guiding Surgical Strategy in Spinal Cord Ependymoma Resection. [PDF]

Neurosurg Pract
Ramirez-Ferrer E, McCutcheon IE, Kimchi G, Amini B, Andrade Almeida R, Call-Orellana F, Zuluaga-Garcia JP, North RY, Alvarez-Breckenridge CA, Weinberg JS, Rhines LD, Tatsui CE.   +11 more
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Comparative outcomes of spinal cord stimulation for neuropathic pain: peripheral nerve versus spinal cord lesions. [PDF]

Neurosurg Rev
Fitzrol DN, Sitthinamsuwan B, Jirachaipitak S, Euasobhon P, Zinboonyahgoon N, Nunta-Aree S.   +5 more
europepmc   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Monitoring morphometric drift in lifelong learning segmentation of the spinal cord. [PDF]

Imaging Neurosci (Camb)
Naga Karthik E, Bédard S, Valošek J, Aigner CS, Bannier E, Bednařík J, Callot V, Combes A, Curt A, David G, Eippert F, Farner L, Fehlings MG, Freund P, Granberg T, Granziera C, Horn U, Horák T, Humphreys S, Hupp M, Kerbrat A, Kinany N, Kolind S, Kudlička P, Lebret A, Lee LE, Mainero C, Martin AR, McGrath M, Nair G, O'Grady KP, Oh J, Ouellette R, Pfender N, Pfyffer D, Pradat PF, Prat A, Pravatà E, Reich DS, Ricchi I, Rotem-Kohavi N, Schading-Sassenhausen S, Seif M, Smith A, Smith SA, Sweeney G, Tam R, Traboulsee A, Treaba CA, Tsagkas C, Vavasour Z, Van De Ville D, Weber Ii KA, Chandar S, Cohen-Adad J.   +54 more
europepmc   +1 more source