Results 221 to 230 of about 1,618,018 (347)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

The Interplay Between Neuromodulation and Stem Cell Therapy for Sensory-Motor Neuroplasticity After Spinal Cord Injury: A Perspective View. [PDF]

J Clin Med
Yousak A, Jose KA, Gorgey AS.
europepmc   +1 more source

Cord Blood (CB) Extends Transplant Access to Racial and Ethnic Minorities: A Prospective Study of 309 Unrelated Searches in Patients with High-Risk Hematologic Malignancies [PDF]

, 2009
S.S. Lee, Andromachi Scaradavou, Rebecca Hawke, K.A. Webb, Deborah Wells, Michelle Abboud, Evangelos Papadopoulos, Nancy A. Kernan, Juliet N. Barker   +8 more
openalex   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy.

JAMA Neurol
Tanaka H, Black LE, Forrest SL, Danics K, Sadia N, Khodadadi M, Tator C, Smith DH, Tartaglia MC, Stewart W, Kovacs GG.   +10 more
europepmc   +1 more source

Saccular Limited Dorsal Myeloschisis with a Short Stalk at the Base of the Sac Causing Spinal Cord Deviation out of the Spinal Canal. [PDF]

NMC Case Rep J
Morioka T, Kanata A, Amano T, Inoue D, Suzuki SO, Shimogawa T, Mukae N, Yoshimoto K.   +7 more
europepmc   +1 more source

Patterns of collateral arteries to the spinal cord after thoraco-abdominal aortic aneurysm repair [PDF]

Daiki Saitoh, Yuya Yamazaki, Tatsunori Tsuji, Naoya Sakoda, Kazuki Yakuwa, Azuma Tabayashi, Junichi Koizumi, A. Ohsawa, Hajime Kin   +8 more
openalex   +1 more source

Graft-Specific HLA-Antibodies Do Not Influence Unit Dominance and Do Not Prevent High Rates of Sustained Donor Engraftment in Recipients of Double-Unit Cord Blood (CB) Transplantation [PDF]

, 2013
Parastoo B. Dahi, Jonathan Barone, Susan H. Hsu, Courtney Byam, Marissa Lubin, Katherine Evans, Doris M. Ponce, Sergio Giralt, Nancy A. Kernan, Andromachi Scaradavou, Juliet N. Barker   +10 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source