Results 231 to 240 of about 1,598,812 (348)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Stitching brain and spinal cord DTI using cross-correlation registration: toward an atlas of spinal tracts. [PDF]

Eur Radiol Exp
Dauleac C, Boukhari A, Jacquesson T, Criton G, Cotton F, Frindel C.   +5 more
europepmc   +1 more source

DNA damage and repair system in spinal cord ischemia [PDF]

, 2003
Ruxian Lin, Glen S. Roseborough, Yu Jia Dong, George M. Williams, Chiming Wei   +4 more
openalex   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Spinal cord metabolism in multiple sclerosis: a decade of missed opportunities and future directions. [PDF]

Spinal Cord
Rudroff T.
europepmc   +1 more source

Needle‐free, Liquid Metal‐embedded Electrospray Deposition System for Controlled Microdroplet Printing

Advanced Science, EarlyView.
The liquid metal‐embedded electrospray deposition (LM‐ESD) system combines stable droplet spray, clog‐free and recoverable operation, and simplified fabrication in a single polydimethylsiloxane (PDMS) microfluidic platform. By eliminating external electrodes, it offers needle‐free, robust, and scalable droplet array printing, ensuring reproducibility ...
Chaeyeong Kang, Seokbeom Roh, Hyunjun Park, Sugeun Lee, Taeha Lee, Sang Won Lee, Hansung Kim, Jinsung Park, Gyudo Lee, Insu Park   +9 more
wiley   +1 more source

Advancing Precision Medicine in Degenerative Cervical Myelopathy. [PDF]

J Clin Med
Al-Shawwa A, Cadotte DW.
europepmc   +1 more source

Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug‐Releasing Capability for the Programmable Repair of Spinal Cord Injury

Advanced Science, EarlyView.
A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei, Susu Huang, Wencan Zhang, Jiayao Wen, Xiaolong Zhou, Wei He, Xiaoye Yang, Haifeng Wang, Guangxi Zhai, Bin Shi, Lin Jin, Dachuan Wang, Shiqing Feng, Lei Ye   +13 more
wiley   +1 more source

Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway. [PDF]

FASEB J
Ren L, Chen Y, Xia J, Song X, Tao L, Li J, Xu L, Lü H, Hu J.   +8 more
europepmc   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source