Results 301 to 310 of about 1,931,209 (398)

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

Advanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang, Ruizhi Lai, Xinpei Wang, Xu Chen, Youjian Zhou, Shengbin Li, Xiaohui Qiu, Zekai Zeng, Jianye Yuan, Jinghuan Mao, Zhidong Chen, Junqing Wang   +11 more
wiley   +1 more source

True Double Umbilical Cord Knots with Good Fetal Outcome: An Incidental Finding on Delivery. [PDF]

Int Med Case Rep J
Ssebwami L, Kiptoo KA, Nabirye JD, Ayebare I, Byonanuwe S.   +4 more
europepmc   +1 more source

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

Advanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao, Xue Zhang, Xiao‐Juan Liu, Yi‐Ling Sun, Cui Yin, Dong‐Liang Tang, Cheng Xiao, Chunyi Zhou   +7 more
wiley   +1 more source

Predictive Factors for Postoperative Outcomes of Cervical Spondylotic Myelopathy in Individuals With Cerebral Palsy. [PDF]

Global Spine J
Lee SJ, Hwang J, Kang MG, Cho M, Ha Y, Cho SR.   +5 more
europepmc   +1 more source

On the Influence of the Cervical Portions of the Sympathetic Nerve and Spinal Cord upon the Eye and its Appendages, illustrated by Clinical Cases, with Observations. [PDF]

John W. Ogle
openalex   +1 more source

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

Advanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster, Prashant Sankaran, Eloise Bihar   +2 more
wiley   +1 more source

Arachnoid Web With Atypical Imaging Findings and Clinical Manifestations: A Case Report. [PDF]

Cureus
Onishi E, Sakamoto Y, Mitsuzawa S, Sako D, Yasuda T.   +4 more
europepmc   +1 more source

High‐Performance Conductive Elastomers Based on Deep Eutectic Solvents and Polyvinyl Alcohol for Flexible Monitoring Sensors

Advanced Electronic Materials, EarlyView.
A novel conductive elastomer is developed by incorporating deep eutectic solvents into a PVA/Polyacrylic Acid (PAA) network. The synergistic effects of dynamic hydrogen bonds, ionic interactions, and chemical crosslinking result in a highly flexible and dense polymer structure, while the integration of sodium chloride ensures excellent conductivity and
Pinwen Wang, Shouhua Han, Zhipeng Hou, Sihang Ren, Muxin Zhao, Liqun Yang   +5 more
wiley   +1 more source

Intravenous infusion of mesenchymal stem cells increased axonal signal intensity in the rubrospinal tract in spinal cord injury. [PDF]

Mol Brain
Hirota R, Sasaki M, Teramoto A, Yamashita T, Kocsis JD, Honmou O.   +5 more
europepmc   +1 more source

Delayed versus Immediate Cord Clamping in Preterm Infants

New England Journal of Medicine, 2017
W. Tarnow-Mordi, J. Morris, A. Kirby, K. Robledo, L. Askie, Rebeccah L. Brown, N. Evans, S. Finlayson, M. Fogarty, V. Gebski, Alpana Ghadge, W. Hague, D. Isaacs, M. Jeffery, A. Keech, M. Kluckow, Himanshu Popat, L. Sebastian, K. Aagaard, M. Belfort, M. Pammi, M. Abdel-latif, G. Reynolds, Shabina Ariff, Lumaan Sheikh, Yan Chen, P. Colditz, H. Liley, M. Pritchard, D. De Luca, K. de Waal, P. Forder, L. Duley, W. El-Naggar, A. Gill, J. Newnham, K. Simmer, K. Groom, P. Weston, Joanna E. Gullam, H. Patel, G. Koh, K. Lui, N. Marlow, S. Morris, A. Sehgal, E. Wallace, R. Soll, Leslie W. Young, D. Sweet, S. Walker, A. Watkins, I. Wright, D. Osborn, J. Simes   +54 more
semanticscholar   +1 more source