Rho GTPase Signaling in Health and Disease: A Complex Signaling Network
Rho GTPases are a family of small G-proteins of the Ras superfamily [...]
Cord Brakebusch
doaj +1 more source
Quantum and Classical Superballistic Transport in a Relativistic Kicked-Rotor System
As an unusual type of anomalous diffusion behavior, superballistic transport is not well known but has been experimentally simulated recently. Quantum superballistic transport models to date are mainly based on connected sublattices which are constructed
Gong, Jiangbin +2 more
core +1 more source
Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]
Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin +7 more
core +1 more source
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
There are many problems with temporal continuity, but there is a hard one for those philosophers who believe that the world is existentially dynamical. In particular, this holds for those who take seriously the requirement that in such a world must vary ...
Cord Friebe
doaj +1 more source
Multilevel Network Games [PDF]
We consider a multilevel network game, where nodes can improve their communication costs by connecting to a high-speed network. The $n$ nodes are connected by a static network and each node can decide individually to become a gateway to the high-speed ...
Abshoff, Sebastian +3 more
core +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
The ratchet effect in a two lag setting and the mitigating influence of yardstick competition [PDF]
In order to increase efficiency in the provision of power distribution networks, the German regulator Bundesnetzagentur plans to implement revenue cap regulation together with yardstick competition.
Cord Brockmann
core +3 more sources
Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury [PDF]
Demyelination contributes to the dysfunction after traumatic spinal cord injury (SCI). We explored whether the combination of neurotrophic factors and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance ...
Cao, Qilin +11 more
core +1 more source
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando +13 more
wiley +1 more source

