Results 41 to 50 of about 1,593,330 (305)

Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

open access: yesCells, 2021
Rho GTPases are a family of small G-proteins of the Ras superfamily [...]
Cord Brakebusch
doaj   +1 more source

Quantum and Classical Superballistic Transport in a Relativistic Kicked-Rotor System

open access: yes, 2014
As an unusual type of anomalous diffusion behavior, superballistic transport is not well known but has been experimentally simulated recently. Quantum superballistic transport models to date are mainly based on connected sublattices which are constructed
Gong, Jiangbin   +2 more
core   +1 more source

Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]

open access: yes, 2019
Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin   +7 more
core   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco   +18 more
wiley   +1 more source

Nothing Comes Next

open access: yesPhilosophy Kitchen, 2020
There are many problems with temporal continuity, but there is a hard one for those philosophers who believe that the world is existentially dynamical. In particular, this holds for those who take seriously the requirement that in such a world must vary ...
Cord Friebe
doaj   +1 more source

Multilevel Network Games [PDF]

open access: yes, 2014
We consider a multilevel network game, where nodes can improve their communication costs by connecting to a high-speed network. The $n$ nodes are connected by a static network and each node can decide individually to become a gateway to the high-speed ...
Abshoff, Sebastian   +3 more
core   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

The ratchet effect in a two lag setting and the mitigating influence of yardstick competition [PDF]

open access: yes
In order to increase efficiency in the provision of power distribution networks, the German regulator Bundesnetzagentur plans to implement revenue cap regulation together with yardstick competition.
Cord Brockmann
core   +3 more sources

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury [PDF]

open access: yes, 2010
Demyelination contributes to the dysfunction after traumatic spinal cord injury (SCI). We explored whether the combination of neurotrophic factors and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance ...
Cao, Qilin   +11 more
core   +1 more source

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy