Results 41 to 50 of about 1,931,209 (398)
CRISPR Genome Editing: How to Make a Fantastic Method Even Better
CRISPR genome editing describes targeted mutagenesis involving a programmable DNA scissor consisting of a protein (Cas9) bound to a short RNA [...]
Cord Brakebusch
doaj +1 more source
3-D refractive index tomograms and deformability of individual human red blood cells from cord blood of newborn infants and maternal blood [PDF]
Red blood cells (RBCs) from the cord blood of newborn infants have distinctive functions for fetal and infant development. To systematically investigate the biophysical characteristics of individual cord RBCs in newborn infants, a comparative study was performed of RBCs from cord blood of newborn infants, and of adult RBCs from mothers or non-pregnant ...
arxiv +1 more source
Neuro-axonal injury is a key factor in the development of permanent disability in multiple sclerosis. Neurofilament light chain in peripheral blood has recently emerged as a biofluid marker reflecting neuro-axonal damage in this disease.
Christian Barro+14 more
semanticscholar +1 more source
Aquaporins in the Spinal Cord [PDF]
Aquaporins (AQPs) are water channel proteins robustly expressed in the central nervous system (CNS). A number of previous studies described the cellular expression sites and investigated their major roles and function in the brain and spinal cord. Among thirteen different mammalian AQPs, AQP1 and AQP4 have been mainly studied in the CNS and evidence ...
Michal Oklinski+7 more
openaire +3 more sources
Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits, while spontaneous recovery and therapeutic efficacy are limited.
Shaowei Guo+8 more
semanticscholar +1 more source
We recently reported that the neuropathic pain medication, gabapentin (GBP; Neurontin), significantly attenuated both noxious colorectal distension (CRD)-induced autonomic dysreflexia (AD) and tail pinch-induced spasticity compared to saline-treated ...
Alexander G. Rabchevsky+12 more
doaj +1 more source
Posthumanist Cultural Studies: Taking the Nonhuman Seriously
In recent years, there has been a pronounced (re-)turn to questions of ontology, matter, and realism in the humanities and social sciences. What all these theoretical formations have in common is their profound challenge to human exceptionalism.
Cord Florian
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Towards fully commercial, UV-compatible fiber patch cords [PDF]
We present and analyze two pathways to produce commercial optical-fiber patch cords with stable long-term transmission in the ultraviolet (UV) at powers up to $\sim$ 200 mW, and typical bulk transmission between 66-75\%. Commercial fiber patch cords in the UV are of great interest across a wide variety of scientific applications ranging from biology to
arxiv +1 more source
Towards contrast-agnostic soft segmentation of the spinal cord [PDF]
Spinal cord segmentation is clinically relevant and is notably used to compute spinal cord cross-sectional area (CSA) for the diagnosis and monitoring of cord compression or neurodegenerative diseases such as multiple sclerosis. While several semi and automatic methods exist, one key limitation remains: the segmentation depends on the MRI contrast ...
arxiv +1 more source