Results 91 to 100 of about 9,787 (201)

Cord blood red cell concentrates for preterm neonate transfusion: Insights from the multicenter BORN trial

open access: yesTransfusion, EarlyView.
Abstract Background The BORN trial suggested that using cord blood‐red blood cells (CB‐RBCs) to transfuse severely preterm neonates significantly improves clinical outcomes compared to standard adult donor RBCs (A‐RBC). Study Design and Methods The study illustrates CB‐RBC concentrate production and inventory management across nine CB banks ...
Claudio Pellegrino   +38 more
wiley   +1 more source

No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals

open access: yesExperimental Physiology, EarlyView.
Abstract Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure that are mirrored by middle cerebral artery blood velocity (MCAv). However, whether lower‐ or upper‐body RE elicits a differential cerebrovascular response has not yet been examined.
Stephanie Korad   +2 more
wiley   +1 more source

COMPARISON OF EARLY AND DELAYED UMBILICAL CORD CLAMPING IN THE THIRD STAGE OF LABOUR

open access: yesZdravniški Vestnik, 2015
Background: Umbilical cord clamping in the third stage of labour is still controversial. Early cord clamping is defined as clamping at 10, 15, 30 or 60 seconds after delivery and delayed as clamping after 60 seconds or at 2-5 minutes after delivery, when
Tamara Serdinšek   +2 more
doaj  

Blue plaque review series: Thomas Graham Brown: Before his time

open access: yesExperimental Physiology, EarlyView.
Abstract Thomas Graham Brown made a seminal discovery, published in 1911 while he was a Carnegie Fellow in the University of Liverpool laboratory of Nobel Prize winner Charles S. Sherrington. Working in cats, he showed that rhythmic ‘voluntary’ behaviour, such as stepping and, by inference, walking, does not result from a chain of reflex events, but ...
Ronald L. Calabrese, Eve Marder
wiley   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall   +8 more
wiley   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero   +5 more
wiley   +1 more source

A dermatosurgically optimized ear tamponade technique to prevent external auditory canal obstruction – a method for secure closure

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Martin Flatz   +2 more
wiley   +1 more source

TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain‐like behaviors in rats with neuropathic pain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez   +7 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman   +2 more
wiley   +1 more source

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