Results 121 to 130 of about 11,066 (216)

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu   +10 more
wiley   +1 more source

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen   +13 more
wiley   +1 more source

Obstetrical and neonatal factors associated with optimal public banking of umbilical cord blood in the context of delayed cord clamping

open access: bronze, 2019
Anna Munro   +7 more
openalex   +2 more sources

Topology Optimization of Exo‐Glove Poly II for Enhancing Functionality and Wearability

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 1, January 2026.
This study proposes a topology optimization method for Exo‐Glove Poly II to enhance functionality and wearability. By modeling its finger body as a longitudinally periodic structure, a unit cell‐level optimization—aimed at minimizing distortion and achieving user‐preferred stretchability—is established. Experimental validation shows reduced distortion,
Soomin Choi   +4 more
wiley   +1 more source

940: Evaluation of implementation of a delayed cord clamping protocol for premature infants in a high volume maternity center [PDF]

open access: bronze, 2016
Lilly Y. Liu   +4 more
openalex   +1 more source

Baishaoluoshi Decoction Mitigates Post‐Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo‐A/NgR Signaling Pathway

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
Baishaoluoshi Decoction alleviates post‐stroke spasticity by downregulating inhibitory proteins (Nogo‐A/NgR) in the peri‐infarct brain region and reducing NgR/Olig2 co‐localization in oligodendrocytes, thereby enhancing synaptic plasticity. ABSTRACT Objective: This study systematically investigated the effects and molecular mechanisms of Baishaoluoshi ...
Xiongxing Sun   +11 more
wiley   +1 more source

PGC‐1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti‐Inflammatory Response

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
ChREBP transcriptionally regulates PGC‐1α, which enhances the expression of fatty acid oxidation genes, promotes the fatty acid oxidation process, and thereby increases the polarization of anti‐inflammatory microglia, reduces the level of inflammatory factors, and improves pain symptoms.
Ziwei Hu   +15 more
wiley   +1 more source

Therapeutic Effects of Nizubaglustat in a Mouse Model of GM2 Gangliosidosis

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Nizubaglustat is a novel selective inhibitor of glucosylceramide synthase (GCS) and the non‐lysosomal glucocerebrosidase (NLGase, GbA2) with brain penetrant properties. It is currently in clinical development as an oral treatment for rare lysosomal storage diseases with neurological involvement. One such disease group called GM2 gangliosidosis,
Kyle Landskroner   +3 more
wiley   +1 more source

Effect of maternal oxytocin on umbilical venous and arterial blood flows during physiological-based cord clamping in preterm lambs

open access: gold, 2021
Fiona J. Stenning   +11 more
openalex   +2 more sources

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