Results 41 to 50 of about 11,066 (216)

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Knowledge and Practice of Umbilical Cord Clamping among Maternity Care Providers [PDF]

Journal of Midwifery & Reproductive Health, 2018
Background & aim: Based on the current scientific evidence, delayed cord clamping (DCC) elevates early hemoglobin concentrations and iron stores in the neonate. However, the persistent practice of early cord clamping (ECC) is still a routine care.
Girija Madhavanprabhakaran, Allende Wittmann, Gowri Vaidyanathan, Tamima Aldughaishi, Deepa Shaji Thomas   +4 more
doaj   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Circulating prostaglandin E2 concentrations decrease at birth in premature lambs

Frontiers in Pediatrics
RationaleDuring pregnancy, prostaglandin E2 (PGE2) is released from the placenta and circulates in relatively high concentrations in the fetus. As PGE2 suppresses breathing, PGE2 concentrations must decrease after birth, but the timing and mechanisms ...
Timothy J. R. Panneflek, Janneke Dekker, Kelly J. Crossley, Kelly J. Crossley, Cailin Diedericks, Cailin Diedericks, Kristel L. A. M. Kuypers, Ebony R. Cannata, Ebony R. Cannata, Paige J. Riddington, Paige J. Riddington, Femmie E. Bloem, Alison M. Thiel, Alison M. Thiel, Thomas van den Akker, Thomas van den Akker, Graeme R. Polglase, Graeme R. Polglase, Arjan B. te Pas, Stuart B. Hooper, Stuart B. Hooper, Indya M. Davies, Indya M. Davies   +22 more
doaj   +1 more source

To clamp or not to clamp late?

Journal of Pediatric and Neonatal Individualized Medicine, 2013
When resuscitating a neonate, one encounters controversial issues and a great deal of confusion. These issues include the question as to when should the umbilical cord be clamped.
Nicoletta Iacovidou, Aggeliki Syggelou, Theodoros Xanthos   +2 more
doaj   +1 more source

Characteristics and physiological basis of falls in ventricular outputs after immediate cord clamping at delivery in preterm fetal lambs [PDF]

, 2021
Joseph J. Smolich, Kelly R. Kenna, Sarah Phillips, Jonathan P. Mynard, Michael Cheung, Gavin Lambert   +5 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Comparing delayed cord clamping and umbilical cord milking during elective cesarean section for the neonatal outcome

European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2023
Objectives: to compare between immediate cord clamping, delayed cord clamping, and umbilical cord milking and their effects on hemoglobin and bilirubin level in term infants in cesarean section.
Tamer A. Hosny, Amal Z. Azzam, Mohga Ashraf Said, Bahaa Salah Hammad   +3 more
doaj   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source