Results 161 to 170 of about 97,898 (297)
Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease
Alimentary Pharmacology &Therapeutics, EarlyView.In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.Ana Garre, Andrea Nuñez Ortiz, Saioa Rubio, María Teresa Diz‐Lois Palomares, Sabino Riestra, Horacio Alonso‐Galán, Estela Fernández‐Salgado, Rocío Ferreiro‐Iglesias, Milagros Vela, Ángel Ponferrada Díaz, Eugenia Sánchez Rodríguez, Vicent Hernández, Lara Arias García, Jesús Barrio, José María Huguet, Daniel Ginard, Montserrat Rivero, Isabel Vera, Inmaculada Alonso‐Abreu, José Manuel Benítez, Mariam Aguas, Iago Rodríguez‐Lago, Xavier Calvet, Luis Fernández‐Salazar, Ana Echarri, María Teresa Arroyo, Mercè Navarro‐Llavat, Pablo Vega, Mónica Sierra, Elena Guerra del Río, Raquel Vicente, María José Casanova, Pablo Navarro, Jone Ortiz de Zarate, Pilar Varela Trastoy, Katerina Spicakova, Ana Gutiérrez, María Dolores Martín‐Arranz, Concepción Piñero, Álvaro Hernández‐Martínez, Emilio Torrella Cortés, José Miguel Marrero, Rufo H. Lorente Poyatos, Lidia Martí Romero, Orencio Bosch, José María Duque, Montserrat Aceituno, Hipólito Fernández, Belén Crespo Suarez, Ana María Fuentes Coronel, Liliana Pozzati, Pilar Robledo, Eva Sesé Abizanda, Belén Herreros Martínez, Nuria Jiménez, Pilar López Serrano, Manuela Josefa Sampedro, Fernando Bermejo, Alfredo J. Lucendo, Margarita Muñoz Vicente, Margarita Menacho, José Joaquín Ramírez Palanca, Raquel Camargo, Amalia Carmona, Sandra Torra Alsina, Margalida Calafat, José Luis F. Forcelledo, Juan Nerín de la Puerta, Isabel Nicolás, Verónica Opio, Yolanda Ber, Abdel Bouhmidi, Alfredo Abraldes Bechiarelli, Carlos Castaño‐Milla, Noelia Cruz, Jordi Gordillo, Amparo Sapiña, Alina López, Silvia Rodríguez Mondéjar, María Teresa Novella Durán, Belén Botella, Marcos Kutz, Lilyan Kolle, Ignacio Marín‐Jiménez, Francisco J. Martínez‐Cerezo, Rebeca Irisarri, Eduardo Iyo, Óscar Roncero, Miriam Sabat, Yolanda Torres Domínguez, Cesar Ledezma, Eva María Zapata, María José Alcalá, Laia Lluis, Cristina Martínez Pascual, Isabel Blázquez Gómez, Luis Hernández, Laura Mata, Ana Monrobel, Alejandro Hernández Camba, Nuria Maroto, María Tejada, María Luisa Galve, María Montealegre, Daniel Hervías, Marta Soler, José Antonio Gómez‐Valero, Manuel Barreiro‐de Acosta, Pilar Soto Escribano, José Luis Cabriada, Daniel Ceballos, Maria Esteve, Alba García Rodríguez, Vanesa Royo, Fernando Gomollón, Cristina Verdejo Gil, Pilar Nos, Ruth de Francisco, María José García, Carmen Dueñas Sadornil, Cristina Rodríguez, Beatriz Sicilia, Borja M. Fernandez‐Felix, Javier P. Gisbert, María Chaparro, on behalf of the EpidemIBD Group of GETECCU, Alfredo Abraldes Bechiarelli, José Manuel Benítez, María del Rosario Calderón, Raquel Camargo, Álvaro Hernández‐Martínez, Eva Iglesias Flores, Eduardo Leo Carnerero, Sandra Marín Pedrosa, Ana Monrobel, Andrea Núñez Ortiz, Natalia Ruiz Santana, María Tejada, Yolanda Torres Domínguez, María José Alcalá, Erika Alfambra, Yolanda Ber, Fernando Gomollón, Miguel Montoro, Juan Manuel Nerín, Elena Peña, Raquel Vicente, José María Duque, Ruth de Francisco, Alejo Mancebo Mata, Susana Martínez González, Isabel Pérez Martínez, Sabino Riestra, Pilar Varela Trastoy, Inmaculada Alonso‐Abreu, Daniel Ceballos, Noelia Cruz, Elena Guerra del Río, Alejandro Hernández Camba, Lilian Kole, José Miguel Marrero, Nuria Pérez, Marta Soler, Milagros Vela, José Luis F Forcelledo, Montserrat Rivero, Rufo Lorente Poyatos, Cristina Verdejo Gil, María Montealegre, Alfredo J Lucendo, Óscar Roncero, Abdel Bouhmidi, Daniel Hervías, Lara Arias García, Jesús Barrio, Ana Y Carbajo, Luis Fernández‐Salazar, Paola Fradejas, Ana María Fuentes Coronel, Luis Hernández, Carmen López Ramos, Laura Mata, Concepción Piñero, Beatriz Sicilia, Mónica Sierra, Mónica Vásquez, Montserrat Aceituno, Michelle Bautista, Xavier Calvet, Maria Esteve Comas, Antonia Montserrat, José Antonio Gómez Valero, Jordi Gordillo, Cesar Ledezma, Laia Lluis, Francisco J. Martínez‐Cerezo, Margarita Menacho, Mercè Navarro‐Llavat, Silvia Rodríguez Mondéjar, Miriam Sabat, Manuela Josefa Sampedro, Eva Sesé Abizanda, Anibal Silva, Sandra Torra Alsina, Leyanira Torrealba, Carmen Vila Lolo, Marta Ágreda Chinea, Alicia Algaba, Fernando Bermejo, Isabel Blázquez Gómez, Orencio Bosch, Belén Botella, María José Casanova, Carlos Castaño‐Milla, María Chaparro, Rocío De Lucas, Mercedes Domínguez‐Antonaya, María G Donday, Almudena Durán, María Luisa Galve, Laura García Ramírez, Ana Garre, Javier P. Gisbert, Iván Guerra, Paloma Jiménez, Beatriz López Cauce, Antonio López‐Sanromán, Pilar López Serrano, Ignacio Marín‐Jiménez, María Dolores Martín‐Arranz, José Antonio Olmos Jerez, Verónica Opio, José Lázaro Pérez Calle, Rocío Plaza Santos, Ángel Ponferrada Díaz, Elena San Miguel, Eugenia Sánchez Rodríguez, Isabel Vera‐Mendoza, Mariam Aguas, Marífé García‐Sepulcre, Ana Gutiérrez, Belén Herreros Martínez, José María Huguet, Nuria Jiménez, Nuria Maroto, Lidia Martí Romero, Miguel Mínguez, Margarita Muñoz Vicente, Pablo Navarro, Pilar Nos, José Joaquín Ramírez Palanca, Marisa Roldán Lafuente, Liliana Pozzati, Pilar Robledo, Manuel Barreiro‐de Acosta, Iria Bastón –Rey, Amalia Carmona, Daniel Carpio, Elena Castro, Belén Crespo Suarez, María Teresa Diz‐Lois Palomares, Ana Echarri, Jesús Daniel Fernández‐de Castro, Estela Fernández Salgado, Rocío Ferreiro‐Iglesias, Vicent Hernández, Alina López Baz, Pablo Pérez Galindo, María Jesús Ruiz Barcia, Pablo Vega, Margalida Calafat, Daniel Ginard, Eduardo Iyo, María Teresa Novella Durán, Josep Reyes, Carolina Rodríguez Hidalgo, Vanesa Royo, Amparo Sapiña.r, Ana Belen Aliende, Hipólito Fernández Rosáenz, María Fraile González, Alba García Rodríguez, Berta Lapeña Muñoz, María Teresa Moyano, Susana Revuelta Martínez, Rebeca Irisarri, Marcos Kutz, Óscar Nantes, Cristina Rodríguez, Saioa Rubio, Miren Vicuña, Horacio Alonso, Jose Luis Cabriada, Agustin Castiella Eguzkiza, Itziar Galdona, Ainara Maíz, Ana Isabel Muñagorri Santos, Nerea Muro Carral, Jone Ortiz de Zarate, Nora Otegui, Iago Rodríguez‐Lago, Katerina Spicakova, Eva María Zapata, Leire Zubiaurre Lizarralde, Jose Manuel Castillo Espinosa, María del Carmen Martínez Bonil, Cristina Martínez Pascual, Isabel Nicolás, Emilio Torrella Cortés +308 morewiley +1 more sourceRevisiting Ferritin‐IgG Score to Predict Complete Biochemical Response in Autoimmune Hepatitis
Alimentary Pharmacology &Therapeutics, EarlyView.The ferritin‐IgG score failed external validation in a large Spanish multicentre cohort. However, baseline IgG ≥ 1.89×ULN independently predicted both complete biochemical response and biochemical response (defined as transaminase normalization), identifying patients less likely to achieve timely remission with standard therapy.Álvaro Díaz‐González, Bastian Engel, Manuel Hernández‐Guerra, Indhira Pérez‐Medrano, Beatriz Mateos, Rosa M. Morillas, Elena Gómez, Judith Gómez, Diana Horta, Isabel Conde, María Del Barrio, Ignasi Olivas, Ismael El Hajra, Mar Riveiro‐Barciela, Ana Barreira‐Díaz, Carmen López, Carmen Álvarez‐Navascúes, Manuel Rodríguez Perálvarez, Elmar Jaeckel, Richard Taubert, María‐Carlota Londoño +20 morewiley +1 more sourceThe TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population
Alimentary Pharmacology &Therapeutics, EarlyView.In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.José M. Remes‐Troche, Luis Raúl Valdovinos‐García, C. Prakash Gyawali, José Luis Vargas‐Basurto, Carlos Alberto Reyes‐Medina, Gisselle Vanessa González‐Hernández, A. Rafael Bernal Mendez, H. H. Barragán Cordova, Pablo Thomas‐Dupont, Peter Grube‐Pagola +9 morewiley +1 more sourceThe c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment
British Journal of Pharmacology, EarlyView.Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.Samuel Singleton, Fraser Nunn, Erika Lace, Álvaro Lorente‐Macías, Rachel Toth, Asier Unciti‐Broceta, Tim G. Hales +6 morewiley +1 more sourceBehaviour Support in Dentistry Core Outcomes (BeSiDe‐CO): A Core Outcome Set Development Study
Community Dentistry and Oral Epidemiology, EarlyView.ABSTRACT Objectives
To develop a Core Outcome Set suitable for adults and children for use in studies of Dental Behaviour Support (DBS) techniques, including non‐pharmacological DBS, sedation and General Anaesthesia research. Methods
Two systematic reviews generated a preliminary list of candidate outcomes that were shared with Key Stakeholders (KSG ...Caoimhin Mac Giolla Phadraig, Isabel C. Olegário, Shaelynn Hsu, Maryam Al Zayer, Aisyah Binti Ahmad Fisal, Alison Dougall, Gareth B. Kitchen, Henry F. Duncan, Sarah Baker, Sharat Pani, Sreekanth Kumar Mallineni, Mandy Daly, The BeSiDe COS Collaboration, Tracey Scott, Carolyn Akintola, Éilish Burke, Steve Moore, Barbara Vallo, Jacobo Posse Limerese, Karin Alexandra Van Nes, Maiken Bagger, Olive Healy, Andrew Geddis‐Regan +22 morewiley +1 more source
