Results 81 to 90 of about 284,987 (280)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A facet atlas: Visualizing networks that describe the blends, cores, and peripheries of personality structure.

open access: yesPLoS ONE, 2020
We created a facet atlas that maps the interrelations between facet scales from 13 hierarchical personality inventories to provide a practically useful, transtheoretical description of lower-level personality traits. We generated this atlas by estimating
Ted Schwaba   +3 more
doaj   +1 more source

A Simplified Approach to Analyzing Multi-regional Core-Periphery Models [PDF]

open access: yes
This paper shows that the evolutionary process of spatial agglomeration in multi-regional core-periphery models can be explained analytically by a much simpler method than the continuous space approach of Krugman (1996). The proposed method overcomes the
Akamatsu, Takashi, Takayama, Yuki
core   +1 more source

Peripherality and the impact of SME takeovers [PDF]

open access: yes, 2012
New Economic Geography models typically predict centripetal economic development. One process by which this might be brought about is if large companies based in the core of the economy buy up and remove small dynamic enterprises from peripheral regions,
Cardiff University   +2 more
core  

The Behavior of Epidemics under Bounded Susceptibility

open access: yes, 2014
We investigate the sensitivity of epidemic behavior to a bounded susceptibility constraint -- susceptible nodes are infected by their neighbors via the regular SI/SIS dynamics, but subject to a cap on the infection rate. Such a constraint is motivated by
Banerjee, Siddhartha   +2 more
core   +1 more source

A relational view of Psychological Empowerment and Sense of Community in academic contexts: a preliminary study [PDF]

open access: yes, 2019
Scholars need to pay attention to understand the factors that shape the interactions between individuals and social groups. Constructs like Psychological Sense of Community (PSoC) and Psychological Empowerment (PE) are powerful constructs used to ...
Ramos Vidal, Ignacio
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Coupling of urbanization and eco-environmental quality in the evolution of human-environment relationships in China’s metropolitan regions [PDF]

open access: yesZiyuan Kexue
[Objective] Metropolitan regions, as important carriers of highly concentrated resources and development factors, face numerous ecological and environmental challenges in the process of urbanization. Based on the human-environment relationship, analyzing
LUO Junqiang, ZHANG Zining, ZHANG Peilei, CHANG Genying
doaj   +1 more source

The impact of interregional and intraregional transportation costs on industrial location and efficient transport policies [PDF]

open access: yes
Almost all models of the (New) Economic Geography have focused on interregional transportation costs to understand industrial location, considering regions as dots without intraregional transportation costs.
André De Palma   +2 more
core  

Hydroxyl as a Tracer of H2 in the Envelope of MBM40

open access: yes, 2012
We observed 51 positions in the OH 1667 MHz main line transitions in the translucent, high latitude cloud MBM40. We detected OH emission in 8 out of 8 positions in the molecular core of the cloud and 24 out of 43 in the surrounding, lower extinction ...
Blitz   +28 more
core   +1 more source

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