Results 71 to 80 of about 244,140 (306)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Chest Soft Tissue Schwannoma: a Difficult Case of Diagnosis

open access: yesВестник рентгенологии и радиологии
The article presents a clinical case of a patient born in 1963, examined and treated at Ostroverkhov Kursk Oncology Scientific and Clinical Center in 2024.
M. V. Perevedentsev   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle biopsy of lung lesions : a single-centre experience with 822 biopsies [PDF]

open access: yes, 2018
Purpose: To determine the risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle lung biopsy (CT-CNB). Material and methods: Variables that could increase the risk of pneumothorax and chest tube placement were ...
Gokalp, Gokhan   +3 more
core   +1 more source

Impact of Surgeon’s Experience in Rigid versus Elastic MRI/TRUS-Fusion Biopsy to Detect Significant Prostate Cancer Using Targeted and Systematic Cores [PDF]

open access: gold, 2022
Magdalena Görtz   +12 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies

open access: yesBMC Cancer, 2011
Background An increasing number of neo-adjuvant breast cancer studies are being conducted and a novel model for tumor biological studies, the "window-of-opportunity" model, has revealed several advantages. Change in tumor cell proliferation, estimated by
Ingvar Christian   +8 more
doaj   +1 more source

Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination

open access: yesJournal of Urological Surgery, 2020
Objective:To reveal the significance of core length in current primary transrectal ultrasound-guided prostate biopsy (TRUS-PB) in patients with normal digital rectal examination.Materials and Methods:Data of 3520 patients, who received TRUS-PB between ...
Mesut Altan   +5 more
doaj   +1 more source

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