Results 61 to 70 of about 45,144 (307)

Computed tomography–guided percutaneous transthoracic core needle biopsy for the diagnosis of mediastinal masses

open access: yesThe Journal of Association of Chest Physicians
Mediastinal masses encompass a wide spectrum of diseases; therefore, histopathological diagnosis is crucial for adequate surgical or medical treatments.
Sukanta Kodali   +3 more
doaj   +1 more source

Core needle biopsy in male breast lesions [PDF]

open access: yesJournal of Clinical Pathology, 2003
Aims: To describe results of needle core biopsies of the male breast. Methods: Needle core biopsies from male breasts and corresponding histological follow up data were retrieved from pathology computer files.
openaire   +2 more sources

Research Progress in Wearable Microneedle Sensors for Health Analysis

open access: yesAdvanced Sensor Research, EarlyView.
Wearable biosensors are transforming personal healthcare by enabling minimally invasive, molecular‐level monitoring. Emerging electrochemical microneedle sensors can detect analytes in interstitial fluid, enabling painless extraction and real‐time tracking.
Adnan Zameer   +3 more
wiley   +1 more source

Ultrasound-Guided Core Needle Biopsy for Salivary Gland Lesions

open access: yesGomal Journal of Medical Sciences, 2004
Background: A salivary gland swelling may result from various causes and create a diagnostic challenge. This study was conducted to evaluate the usefulness of ultrasound-guided core needle biopsy as a diagnostic modality.
Syed Qaiser Husain Naqvi   +5 more
doaj  

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan   +11 more
wiley   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

open access: yesAdvanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa   +23 more
wiley   +1 more source

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

open access: yesAdvanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen   +11 more
wiley   +1 more source

Mediastinal follicular dendritic cell sarcoma: a rare, potentially under-recognized, and often misdiagnosed disease

open access: yesDiagnostic Pathology, 2019
Background Mediastinal follicular dendritic cell sarcoma (FDCS) is extremely rare. Due to potential under-recognization of this disease, it happens to be misdiagnosed, especially on core needle biopsy.
You-Li Wu   +7 more
doaj   +1 more source

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