Results 31 to 40 of about 1,049,724 (311)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Field distribution anomalies and dielectric failure mechanisms associated with core surface defects in liquid-insulated power transformers [PDF]

AIP Advances
Core burr defects are latent sources of electric field distortion and insulation degradation in oil-immersed power transformers. To elucidate their physical mechanism and quantitative impact, this study combines finite element analysis and field testing ...
Hui Xu, Hao Zhan, Hang Jiang, Mengna Liu, Wen Zhou, Lifeng Cheng, Xu Yang   +6 more
doaj   +1 more source

A Long-lived Lunar Magnetic Field Powered by Convection in the Core and a Basal Magma Ocean

The Planetary Science Journal, 2023
An internally generated magnetic field once existed on the Moon. This field reached high intensities (∼10–100 μ T, perhaps intermittently) from ∼4.3 to 3.6 Gyr ago and then weakened to ≲5 μ T before dissipating by ∼1.9–0.8 Gyr ago.
Saira S. Hamid, Joseph G. O’Rourke, Krista M. Soderlund   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Radiated fields by polygonal core-shell nanowires [PDF]

2018 20th International Conference on Transparent Optical Networks (ICTON), 2018
We calculate the electromagnetic field radiated by tubular nanowires with prismatic geometry and infinite length. The polygonal geometry has implications on the electronic localization; the lowest energy states are localized at the edges of the prism and are separated by a considerable energy gap from the states localized on the facets.
Miguel Urbaneja Torres, Anna Sitek, Vidar Gudmundsson, Andrei Manolescu   +3 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Effective Field Theory and the No-Core Shell Model

EPJ Web of Conferences, 2010
In finite model space suitable for many-body calculations via the no-core shell model (NCSM), I illustrate the direct application of the effective field theory (EFT) principles to solving the many-body Schrödinger equation. Two different avenues for fixing
Stetcua I.
doaj   +1 more source

A Fundamental Mechanism of Solar Eruption Initiation in a Multipolar Magnetic Field

The Astrophysical Journal, 2023
Recently, we established a fundamental mechanism of solar eruption initiation in which an eruption can be initiated from a bipolar field through magnetic reconnection in the current sheet (CS) that is formed slowly in the core field as driven by ...
Xinkai Bian, Chaowei Jiang, Xueshang Feng, Pingbing Zuo, Yi Wang   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source