Results 61 to 70 of about 977,559 (266)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Magnetic Fields in Quasar Cores

open access: yesThe Astrophysical Journal, 1998
Multifrequency polarimetry with the Very Long Baseline Array telescope has revealed absolute Faraday rotation measures (RMs) in excess of 1000 rad m-2 in the central regions of the quasars 3C 273, 3C 279, and 3C 380. Beyond a projected distance of ~20 h-1 pc, however, the jets of all three sources are found to have RM < 100 rad m-2.
openaire   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Inductive Approach to Documenting the "Core" and Evolution of the IS Field

open access: yesCommunications of the Association for Information Systems, 2007
This article inductively examines the question of the IS field’s core. We argue that as a socially constructed field, the core aspects of IS can be identified from the work conducted and published by members of the IS community. The abstracts (including titles) of 1,197 IS studies in three premier IS journals for the past 26 years were examined to ...
Jaejoo Lim, Guang Rong, Varun Grover
openaire   +3 more sources

MR imaging quality and feasibility of a novel interleaved iTBS/fMRI setup

open access: yesBrain Stimulation, 2023
Kai-Yen Chang   +7 more
doaj   +1 more source

Magnetic Field Alignment with Dense Cores in the Transition between Cloud and Core Scales

open access: yesThe Astrophysical Journal
In a magnetically dominated model of star formation, we expect to see alignments between the magnetic field orientation of star-forming dense cores and the cloud-scale magnetic field. A. Pandhi et al.
Sean Yin   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Magnetic Field Control Using an Electromagnetic Actuation System with Combined Air‐Core and Metal‐Core Coils

open access: yesAdvanced Intelligent Systems
Magnetic fields are widely utilized for remote control of magnetic objects, with various actuation systems developed for manipulating miniature robots in research and biomedical applications.
Nader Latifi Gharamaleki   +4 more
doaj   +1 more source

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