Results 41 to 50 of about 1,049,724 (311)
At the frequencies used in switching dc-dc converters, the skin and proximity effects have a significant effect on both the losses and leakage inductance of the transformers used in these circuits.
Whitman, Daniel J.
core +1 more source
Geomagnetic Dipole Changes and Upwelling/Downwelling at the Top of the Earth's Core
The convective state of the top of Earth's outer core is still under debate. Conflicting evidence from seismology and geomagnetism provides arguments for and against a thick stably stratified layer below the core-mantle boundary.
Ludovic Huguet +3 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
On the force field optimisation of $$\beta$$-lactam cores using the force field Toolkit
AbstractWhen employing molecular dynamics (MD) simulations for computer-aided drug design, the quality of the used force fields is highly important. Here we present reparametrisations of the force fields for the core molecules from 9 different $$\beta$$ β -lactam classes, for which we utilized the force field Toolkit ...
Qiyang Wu +6 more
openaire +2 more sources
The Earth\u27s geomagnetic field reverses its polarity at irregular time intervals. However, it is not clear whether a reversal is a deterministic (low-dimensional) or a random (high-dimensional) process; the duration-frequency distribution of the ...
Cortini, Massimo, Barton, Christopher C.
core +1 more source
Quantum Omni-Synthesis I: Core Field-Theoretical Framework
The Quantum Omni-Synthesis (QOS) framework is inspired by the cosmological constant problem, the dark sector, and the tension that arises when gravity is treated as purely geometrical while quantum fields remain defined on a fixed background.
Stefalo Acha
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On the equivalence of the hybrid particle–field and Gaussian core models
Hybrid particle–field molecular dynamics is a molecular simulation strategy, wherein particles couple to a density field instead of through ordinary pair potentials. Traditionally considered a mean-field theory, a momentum and energy-conserving hybrid particle–field formalism has recently been introduced, which was demonstrated to approach the Gaussian
Morten Ledum +3 more
openaire +3 more sources

