Results 31 to 40 of about 977,559 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Outer Core Stratification From the High Latitude Structure of the Geomagnetic Field

Frontiers in Earth Science, 2018
The presence of stable stratification has broad implications for the thermal and compositional state of the outer core, the evolution of Earth's deep interior, and the energetics of the geodynamo.
Peter Olson, Peter Olson, Maylis Landeau, Maylis Landeau, Evan Reynolds, Evan Reynolds   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Objectification Features of Social Exclusion and Social Inclusion Categories in the Russian Language (Exemplified by “Glubinka” and “Glush” Concepts)

Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2023
The article is devoted to the consideration of the objectification peculiarities of the social exclusion and social inclusion categories in the territorial aspect in the Russian language on the case of the “glubinka” (“hinterland”) and “glush ...
Nikolay L. Shamne, Marina V. Milovanova
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Field distribution anomalies and dielectric failure mechanisms associated with core surface defects in liquid-insulated power transformers [PDF]

AIP Advances
Core burr defects are latent sources of electric field distortion and insulation degradation in oil-immersed power transformers. To elucidate their physical mechanism and quantitative impact, this study combines finite element analysis and field testing ...
Hui Xu, Hao Zhan, Hang Jiang, Mengna Liu, Wen Zhou, Lifeng Cheng, Xu Yang   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effective Field Theory and the No-Core Shell Model

EPJ Web of Conferences, 2010
In finite model space suitable for many-body calculations via the no-core shell model (NCSM), I illustrate the direct application of the effective field theory (EFT) principles to solving the many-body Schrödinger equation. Two different avenues for fixing
Stetcua I.
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source