Results 61 to 70 of about 922,430 (265)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Experimental study of alternating magnetic field in laminated ferromagnetic core

open access: yesMATEC Web of Conferences, 2018
At engineering simulations of magnetic fields in ferromagnetic cores standard Preisach and Jiles-Atherton models are commonly used. At that a material magnetic properties are considered similar in all points of a core.
Adamyan Yuriy   +2 more
doaj   +1 more source

Mean-field fluid behavior of the Gaussian core model [PDF]

open access: yesPhysical Review E, 2000
We show that the Gaussian core model of particles interacting via a penetrable repulsive Gaussian potential, first considered by Stillinger (J. Chem. Phys. 65, 3968 (1976)), behaves like a weakly correlated ``mean field fluid'' over a surprisingly wide density and temperature range.
Louis, A, Bolhuis, P, Hansen, J
openaire   +5 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Research progress on core self-evaluation in nursing field

open access: yesHuli yanjiu, 2015
It reviewed the concept,structure and measurement of core self-evaluation.It summarized the application of core self-evaluation in the nursing field,so as to provide references for the nursing teaching and nursing management in China.
李璐良, 孙铮, 赵琳琳, 等
doaj  

An Inductive Approach to Documenting the "Core" and Evolution of the IS Field

open access: yesCommunications of the Association for Information Systems, 2007
This article inductively examines the question of the IS field’s core. We argue that as a socially constructed field, the core aspects of IS can be identified from the work conducted and published by members of the IS community. The abstracts (including titles) of 1,197 IS studies in three premier IS journals for the past 26 years were examined to ...
Jaejoo Lim, Guang Rong, Varun Grover
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Magnetic Nanoparticles with Core Shell: Macroscopic Model and Coercive Field

open access: yesAdvances in Materials Science and Engineering, 2010
There exists nonhomogeneous structure in mechanosynthesized nanoparticles consisting of an ordered core surrounded by the shell. The shell may be structurally and magnetically disordered, or it may be ordered.
O. Hudak, M. Hudak
doaj   +1 more source

Effects of the Librationally Induced Flow in Mercury’s Fluid Core with an Outer Stably Stratified Layer

open access: yesThe Planetary Science Journal, 2023
Observational constraints on Mercury’s thermal evolution and magnetic field indicate that the top part of the fluid core is stably stratified. Here we compute how a stable layer affects the core flow in response to Mercury’s main 88 day longitudinal ...
Fleur Seuren   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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