Results 51 to 60 of about 977,559 (266)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Research progress on core self-evaluation in nursing field
It reviewed the concept,structure and measurement of core self-evaluation.It summarized the application of core self-evaluation in the nursing field,so as to provide references for the nursing teaching and nursing management in China.
李璐良, 孙铮, 赵琳琳, 等
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mean-field fluid behavior of the Gaussian core model [PDF]
We show that the Gaussian core model of particles interacting via a penetrable repulsive Gaussian potential, first considered by Stillinger (J. Chem. Phys. 65, 3968 (1976)), behaves like a weakly correlated ``mean field fluid'' over a surprisingly wide density and temperature range.
Louis, A, Bolhuis, P, Hansen, J
openaire +5 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Experimental study of alternating magnetic field in laminated ferromagnetic core
At engineering simulations of magnetic fields in ferromagnetic cores standard Preisach and Jiles-Atherton models are commonly used. At that a material magnetic properties are considered similar in all points of a core.
Adamyan Yuriy +2 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
From Core to Field: Pattern Selection in Dissolving Fractures
Chemical erosion governs the evolution of fractures across Earth systems, which manifests in three distinct dissolution patterns. However, how the boundaries between these regimes depend on system scale remains an open question, and no predictive theory ...
Kai Li +6 more
doaj +1 more source
Magnetic Nanoparticles with Core Shell: Macroscopic Model and Coercive Field
There exists nonhomogeneous structure in mechanosynthesized nanoparticles consisting of an ordered core surrounded by the shell. The shell may be structurally and magnetically disordered, or it may be ordered.
O. Hudak, M. Hudak
doaj +1 more source

