Results 61 to 70 of about 924,283 (264)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Magnetic Field Alignment with Dense Cores in the Transition between Cloud and Core Scales
The Astrophysical JournalIn a magnetically dominated model of star formation, we expect to see alignments between the magnetic field orientation of star-forming dense cores and the cloud-scale magnetic field. A. Pandhi et al.
Sean Yin +9 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Magnetic Fields in Quasar Cores
The Astrophysical Journal, 1998 Multifrequency polarimetry with the Very Long Baseline Array telescope has revealed absolute Faraday rotation measures (RMs) in excess of 1000 rad m-2 in the central regions of the quasars 3C 273, 3C 279, and 3C 380. Beyond a projected distance of ~20 h-1 pc, however, the jets of all three sources are found to have RM < 100 rad m-2.
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
MR imaging quality and feasibility of a novel interleaved iTBS/fMRI setup
Brain Stimulation, 2023 Kai-Yen Chang +7 more
doaj +1 more source
Advanced Intelligent SystemsMagnetic fields are widely utilized for remote control of magnetic objects, with various actuation systems developed for manipulating miniature robots in research and biomedical applications.
Nader Latifi Gharamaleki +4 more
doaj +1 more source
Zhongguo dianli, 2020 The noise of the transformer is mainly generated by the vibration of the oil tank, which is mainly generated by the vibration of the iron core, while the vibration of the iron core is mainly generated by the electromagnetic force.
Chao FAN +7 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source