Results 71 to 80 of about 929,961 (264)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Mercury's Northern Rise Core-Field Magnetic Anomaly. [PDF]
Geophys Res Lett, 2021 Plattner AM, Johnson CL.
europepmc +1 more source
The influence of regularization on the geomagnetic core field modeling
地球与行星物理论评Earth's magnetic field is generated through the dynamo action in the liquid outer core. Using observational data from geomagnetic satellites and observatories, we can construct geomagnetic models that describe spatial and temporal variations of the core ...
Juyuan Xu, Yufeng Lin, Keke Zhang
doaj +1 more source
Analysis and Optimization of Rubber Core Structure of Rotary BOP
Shiyou jixie, 2021 Rotary blowout preventer(BOP)is a key equipment for underbalanced drilling, and its sealing performance is an important factor to ensure safety during operation under pressure. The existing domestic-made rotary BOPs have problems such as weak rubber core
Liu Weimin
doaj
Inverse problem for the Earth's core evolution model
Russian Journal of Earth Sciences, 2020 The size and the age of the inner core impose constraints in modeling of the Earth's core evolution. The origin of the solid core corresponds to the change in convection regime in the core and, correspondingly, to the change in the magnetic field ...
Reshetnyak M Yu
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Direct URCA-processes in neutron star quark core with strong magnetic field.
EPJ Web of Conferences, 2017 Neutrino emissivity in direct URCA processes in superdense strongly magnetized quark medium is calculated. In calculations, we use the covariant method of density matrixes for charge fermions in uniform constant magnetic field.
Belyaev Vasily, Gvozdev Alexander
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Core Knowledge Management in a Designer Community of the Automotive Field [PDF]
, 2008 The competencies in defining design strategies and the know-how necessary to manufacture innovative products are the effective knowledge capital for enterprises that operate in competitive sectors. Within this framework, the paper discusses a conceptual and computational approach to the design of a Core Knowledge Management system that supports people ...
BANDINI, STEFANIA +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source