Results 91 to 100 of about 1,049,724 (311)

Core Knowledge Management in a Designer Community of the Automotive Field [PDF]

, 2008
The competencies in defining design strategies and the know-how necessary to manufacture innovative products are the effective knowledge capital for enterprises that operate in competitive sectors. Within this framework, the paper discusses a conceptual and computational approach to the design of a Core Knowledge Management system that supports people ...
BANDINI, STEFANIA, MANZONI, SARA LUCIA, SARTORI, FABIO   +2 more
openaire   +2 more sources

Detecting the signal cycle of the deep Earth’s dynamic processes based on GRACE satellite and CHAOS-7 model data

Earth and Planetary Physics
The GRACE (Gravity Recovery and Climate Experiment) space mission recorded temporal variation characteristics of the global gravity field at decadal timescales.
YongGang Zhang, ZhengTao Wang, GangHua Ni, ShiZe Zhang   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Mulhollan Field

, 2016
A view of the soccer field, named Mulhollan Field, at Wright State University.https://corescholar.libraries.wright.edu/wsu_historical_photos/1307/thumbnail ...

core  

Field of parked airplanes

, 2015
A view of a field of parked airplanes with several men milling about around them.https://corescholar.libraries.wright.edu/special_ms53_photographs/1233/thumbnail ...

core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

322nd Field Artillery Aiming Cannon

, 2017
Members of the 322nd Field Artillery Division aiming a cannon. Text on back 3 in Field Piece in recoil.https://corescholar.libraries.wright.edu/special_ms100_photographs/1003/thumbnail ...

core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source