Results 71 to 80 of about 9,371,907 (195)

Magnetic Field Control Using an Electromagnetic Actuation System with Combined Air‐Core and Metal‐Core Coils

open access: yesAdvanced Intelligent Systems
Magnetic fields are widely utilized for remote control of magnetic objects, with various actuation systems developed for manipulating miniature robots in research and biomedical applications.
Nader Latifi Gharamaleki   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Analysis and Optimization of Rubber Core Structure of Rotary BOP

open access: yesShiyou jixie, 2021
Rotary blowout preventer(BOP)is a key equipment for underbalanced drilling, and its sealing performance is an important factor to ensure safety during operation under pressure. The existing domestic-made rotary BOPs have problems such as weak rubber core
Liu Weimin
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Inverse problem for the Earth's core evolution model

open access: yesRussian Journal of Earth Sciences, 2020
The size and the age of the inner core impose constraints in modeling of the Earth's core evolution. The origin of the solid core corresponds to the change in convection regime in the core and, correspondingly, to the change in the magnetic field ...
Reshetnyak M Yu
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Using CORE to research outcome measurement [PDF]

open access: yes, 2007
Chris Leach and Mike Lucock have been involved with CORE from its beginning. Jointly responsible for the development of one of the first large databases of the use of CORE in routine clinical practice, they have published a number of key papers looking
Lucock, Mike, Leach, Chris
core   +2 more sources

Element 3 Assessment Report Template Core General Education Assessment, 2017-2018

open access: yes, 2018
The Assessment Report Template for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core   +1 more source

The influence of regularization on the geomagnetic core field modeling

open access: yes地球与行星物理论评
Earth's magnetic field is generated through the dynamo action in the liquid outer core. Using observational data from geomagnetic satellites and observatories, we can construct geomagnetic models that describe spatial and temporal variations of the core ...
Juyuan Xu, Yufeng Lin, Keke Zhang
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy