Results 91 to 100 of about 8,999,290 (232)

Direct URCA-processes in neutron star quark core with strong magnetic field.

open access: yesEPJ Web of Conferences, 2017
Neutrino emissivity in direct URCA processes in superdense strongly magnetized quark medium is calculated. In calculations, we use the covariant method of density matrixes for charge fermions in uniform constant magnetic field.
Belyaev Vasily, Gvozdev Alexander
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Core Knowledge Management in a Designer Community of the Automotive Field [PDF]

open access: yes, 2008
The competencies in defining design strategies and the know-how necessary to manufacture innovative products are the effective knowledge capital for enterprises that operate in competitive sectors. Within this framework, the paper discusses a conceptual and computational approach to the design of a Core Knowledge Management system that supports people ...
BANDINI, STEFANIA   +2 more
openaire   +2 more sources

Element 5 Assessment Plan with Final Report Template Core General Education Assessment, 2021-2022

open access: yes, 2022
The Assessment Plan with Final Report Template for Element 5 - Social Science as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Detecting the signal cycle of the deep Earth’s dynamic processes based on GRACE satellite and CHAOS-7 model data

open access: yesEarth and Planetary Physics
The GRACE (Gravity Recovery and Climate Experiment) space mission recorded temporal variation characteristics of the global gravity field at decadal timescales.
YongGang Zhang   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Element 2 Letter to Chairs from UCOC Core General Education Assessment, 2019-2020

open access: yes, 2020
The Letter to Chairs from UCOC for Element 2 - Mathematics as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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