Results 231 to 240 of about 4,042,841 (387)

CoreDetector: a flexible and efficient program for core-genome alignment of evolutionary diverse genomes. [PDF]

Bioinformatics, 2023
Fruzangohar M, Moolhuijzen P, Bakaj N, Taylor J.   +3 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Additional file 2: Table S2. of Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease

, 2018
Bart Versteeg, Sylvia M. Bruisten, Yvonne Pannekoek, Keith A. Jolley, Martin Maiden, Arie van der Ende, Odile B. Harrison   +6 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Performance of Core Genome Multilocus Sequence Typing Compared to Capillary-Electrophoresis PCR Ribotyping and SNP Analysis of Clostridioides difficile [PDF]

, 2021
Amoe Baktash, Jeroen Corver, Céline Harmanus, Wiep Klaas Smits, Warren N. Fawley, MH Wilcox, Nitin Kumar, David W. Eyre, A. Indra, Alexander Mellmann, EJ Kuijper   +10 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A core-genome multilocus sequence typing scheme for the detection of genetically related Streptococcus pyogenes clusters. [PDF]

J Clin Microbiol, 2023
Toorop MMA, Kraakman MEM, Hoogendijk IV, van Prehn J, Claas ECJ, Wessels E, Boers SA.   +6 more
europepmc   +1 more source

Additional file 2 of The core genome multi-locus sequence typing of Mycoplasma anserisalpingitidis

, 2020
Áron Botond Kovács, Zsuzsa Kreizinger, Barbara Forró, Dénes Grózner, Alexa Mitter, Szilvia Marton, Krisztina Bali, Anna Sawicka, Grzegorz Tomczyk, Krisztián Bànyai, Miklós Gyuranecz   +10 more
openalex   +1 more source

Genome-wide association study of important agronomic traits within a core collection of rice (Oryza sativa L.) [PDF]

, 2019
Peng Zhang, Kaizhen Zhong, Zhengzheng Zhong, Hanhua Tong   +3 more
openalex   +1 more source