Results 71 to 80 of about 3,873,112 (365)

Fast Evolution of Core Promoters in Primate Genomes [PDF]

Molecular Biology and Evolution, 2008
Despite much interest in regulatory evolution, how promoters have evolved remains poorly studied, mainly owing to paucity of data on promoter regions. Using a new set of high-quality experimentally determined core promoters of the human genome, we conducted a comparative analysis of 2,492 human and rhesus macaque promoters and their neighboring nearly ...
Han Liang, Yeong-Shin Lin, Yeong-Shin Lin, Wen-Hsiung Li   +3 more
openaire   +3 more sources

The Metalloprotease, Mpr1, Engages AnnexinA2 to Promote the Transcytosis of Fungal Cells across the Blood-Brain Barrier

Frontiers in Cellular and Infection Microbiology, 2017
Eukaryotic pathogens display multiple mechanisms for breaching the blood-brain barrier (BBB) and invading the central nervous system (CNS). Of the fungal spp., that cause disease in mammals, only some cross brain microvascular endothelial cells which ...
Sarisa Na Pombejra, Michelle Salemi, Brett S. Phinney, Angie Gelli   +3 more
doaj   +1 more source

Proximity-dependent biotin labeling in testicular germ cells identified TESMIN-associated proteins

Scientific Reports, 2022
Characterization of protein–protein interactions (PPI) is a key to understanding the functions of proteins of interest. Recently developed proximity-dependent biotin identification (BioID) has been actively investigated as an alternative PPI mapping ...
Seiya Oura, Akinori Ninomiya, Fuminori Sugihara, Martin M. Matzuk, Masahito Ikawa   +4 more
doaj   +1 more source

Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis [PDF]

, 2011
The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat.
Aerts, A., Antoniw, J., Bailey, A., Bluhm, B., Bowler, J., Bristow, J., Burgt, A., van der, Canto-Canché, B., Churchill, A.C.L., Conde-Ferràez, L., Cools, H.J., Coutinho, P.M., Crane, C.F., Csukai, M., Dehal, P., Dhillon, B., Donzelli, B., Foster, A.J., Geest, H.C., van de, Goodwin, S.B., Grigoriev, I.V., Grimwood, J., Ham, R.C.H.J., van, Hammond-Kosack, K.E., Hane, J.K., Henrissat, B., Kema, G.H.J., Kilian, A., Kobayashi, A.K., Koopmann, E., Kourmpetis, Y., Kuzniar, A., Lee, T.A.J., van der, Lindquist, E., Lombard, V., M'Barek, S., Ben, Maliepaard, C.A., Martins, N., Mehrabi, A., Nap, J.P.H., Oliver, R.P., Ponomarenko, A., Rudd, J.J., Salamov, A., Schmutz, J., Schouten, H.J., Shapiro, H., Stergiopoulos, I., Torriani, S.F.F., Tu, H., Vries, R.P., de, Waalwijk, C., Ware, S.B., Wiebenga, A., Wit, P.J.G.M., de, Wittenberg, A.H.J., Zwiers, L.H.   +56 more
core   +5 more sources

A genome triplication associated with early diversification of the core eudicots [PDF]

Genome Biology, 2012
Abstract Background Although it is agreed that a major polyploidy event, gamma, occurred within the eudicots, the phylogenetic placement of the event remains unclear. Results To determine when this polyploidization occurred relative to ...
Joel R. McNeal, Joel R. McNeal, Pamela S. Soltis, Michael R. McKain, Toni M. Kutchan, Megan Rolf, John E. Bowers, Dennis W. Stevenson, J. C. Pires, Douglas E. Soltis, Eric J. Carpenter, Yuannian Jiao, Daniel R. Ruzicka, Eric K. Wafula, Xiaolei Wu, Yeting Zhang, Michael K. Deyholos, André S. Chanderbali, Norman J. Wickett, Saravanaraj Ayyampalayam, Yong Zhang, Jun Wang, Jun Wang, Gane Ka-Shu Wong, Gane Ka-Shu Wong, Claude W. dePamphilis, Jim Leebens-Mack, Richard W. McCombie   +27 more
openaire   +4 more sources

Genomic Characterization of Lactobacillus delbrueckii Strains with Probiotics Properties

Frontiers in Bioinformatics, 2022
Probiotics are health-beneficial microorganisms with mainly immunomodulatory and anti-inflammatory properties. Lactobacillus delbrueckii species is a common bacteria used in the dairy industry, and their benefits to hosting health have been reported ...
Luís Cláudio Lima De Jesus, Flávia Figueira Aburjaile, Thiago De Jesus Sousa, Andrei Giacchetto Felice, Siomar De Castro Soares, Luiz Carlos Junior Alcantara, Luiz Carlos Junior Alcantara, Vasco Ariston De Carvalho Azevedo   +7 more
doaj   +1 more source

The Neisseria gonorrhoeae Accessory Genome and Its Association with the Core Genome and Antimicrobial Resistance. [PDF]

Microbiol Spectr, 2022
The emergence of antimicrobial resistance (AMR) against third generation cephalosporins in Neisseria gonorrhoeae is a major public health concern, as these are antibiotics of last resort for the effective treatment of gonorrhea.
de Korne-Elenbaas J, Bruisten SM, van Dam AP, Maiden MCJ, Harrison OB.   +4 more
europepmc   +4 more sources

The influence of the accessory genome on bacterial pathogen evolution [PDF]

, 2011
Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity.
Abu-Ali GS, Adiba S, Alfano JR, Arnold DL, Arnold DL, Arnold DL, Asadulghani M, Baharoglu Z, Baquero F, Barash I, Blondel CJ, Blondel CJ, Brüssow H, Cambray G, Chen J, Chen Y, Choi J, Colinon C, Croucher NJ, Dawes FE, De Gelder L, Diard M, Dillon SC, Douard G, Doyle M, Elsaied H, Fondi M, Freeman VJ, Gartemann KH, Gillings MR, Godfrey SAC, Govind R, Greenberg JT, Grillot-Courvalin C, Groisman EA, Guerin E, Hacker J, Hacker J, Halary S, Hassan F, Hazen TH, Hegstad K, Heinemann JA, Heringa S, Hochhut B, Holden MT, Huang L, Imamovic L, Jackson RW, Jackson RW, Jenner C, Joss M, Jové T, Kearney B, Kers JA, Kiiru JN, Koenig JE, Koenig JE, Krauland MG, Landgraf A, Larsson P, Leplae Rl, León G, Lipps HJ, Lloyd AL, Loftie-Eaton W, Lovell HC, Lovell HC, Manning SD, Marchetti M, Matz C, Maurelli AT, Mazel D, Michael CA, Michael CA, Morris CE, Morris CE, Moura A, Naas T, Nadarasah G, Naka H, Nawaz M, Ogura Y, Paauw A, Partridge SR, Pitman A, Poirel L, Poirel L, Ramirez MS, Rankin DJ, Rezzonico F, Rivas LA, Rodriguez-Martinez JM, Rohmer L, Rosewarne CP, Sajjad A, Salanoubat M, Salzberg SL, Seth-Smith H, Shaheen BW, Siguier P, Siguier P, Smillie C, Smith AB, Song H, Sota M, Steinberg KM, Sundin GW, Sundin GW, Tao L, Treangen TJ, van der Meer JR, van der Veen EL, van Essen-Zandbergen A, Wagner A, Waldor MK, Wiesner M, Woodford N, Yang H, Zhou Z, Zupan J   +120 more
core   +2 more sources

A Vibrio cholerae Core Genome Multilocus Sequence Typing Scheme To Facilitate the Epidemiological Study of Cholera

Journal of Bacteriology, 2020
Toxigenic Vibrio cholerae isolates of the O1 and O139 serogroups are the causative agents of cholera, an acute diarrheal disease that plagued the world for centuries, if not millennia.
Kevin Y. H. Liang, F. Orata, M. Islam, T. Nasreen, Munirul Alam, C. Tarr, Y. Boucher   +6 more
semanticscholar   +1 more source

Defining the core essential genome of Pseudomonas aeruginosa [PDF]

Proceedings of the National Academy of Sciences, 2018
Genomics offered the promise of transforming antibiotic discovery by revealing many new essential genes as good targets, but the results fell short of the promise. While numerous factors contributed to the disappointing yield, one factor was that essential genes for a bacterial species were often defined based on a single or limited number
Noam Shoresh, Cristina Penaranda, Tiantian White, Bradley E. Poulsen, Bradley E. Poulsen, Rui Yang, Deborah T. Hung, Deborah T. Hung, Sarah J. Osmulski, Anne E. Clatworthy, Anne E. Clatworthy, Li Li   +11 more
openaire   +3 more sources