Results 1 to 10 of about 18,005,559 (248)

Fast but not furious: a streamlined selection method for genome-edited cells

open access: yesLife Science Alliance, 2021
Magnetic-activated genome-edited cell sorting (MAGECS) allows a fast and easy generation of genetically modified cells. In the last decade, transcription activator-like effector nucleases and CRISPR-based genome engineering have revolutionized our ...
Haribaskar Ramachandran   +4 more
doaj   +1 more source

Improvement of Detection Method of Pasteurella pneumotropica and Its Medical Elimination in Mice

open access: yesShiyan dongwu yu bijiao yixue, 2021
ObjectiveTo modify the method for sensitive detection of Pasteurella pneumotropica in mice in routine monitoring, and to explore the feasibility of medical elimination in Pasteurella pneumotropica infected mice.MethodsThe Pasteurella pneumotropica were ...
ZHANG Tao   +3 more
doaj   +1 more source

Design Factors in Evaluating and Formulating IT Governance Systems in Public Organizations

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2023
The application of information technology (IT) by central and regional governments to public services is intended to efficiently and effectively improve performance and public services. However, many studies have shown the ineffective application of IT.
Muhammad Rifai Katili   +2 more
doaj   +1 more source

Сore Jonsson theories

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2020
The article concerns the description the new concept as core of Jonsson theories, also their combinations, which admit a core model in the class of existentially closed models of this theory.
A.R. Yeshkeyev   +2 more
doaj   +1 more source

Closure of special atomic subsets of semantic model

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2020
The present paper concerns some properties of the so-called small models, generally speaking, not necessarily complete theories and their relationship with each other. In the well-known paper [1], R.
A.R. Yeshkeyev   +2 more
doaj   +1 more source

The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice

open access: yesNature Communications, 2023
The liver lipid metabolism of older individuals canbecome impaired and the circadian rhythm of genes involved in lipid metabolism is also disturbed. Although the link between metabolism and circadian rhythms is already recognized, how these processes are
Jing Wu   +12 more
doaj   +1 more source

Improving the Gaussianity of radar reflectivity departures between observations and simulations using symmetric rain rates [PDF]

open access: yesAtmospheric Measurement Techniques
Given that the Gaussianity of the observation error distribution is the fundamental principle of some data assimilation and machine learning algorithms, the error structure of radar reflectivity has become increasingly important with the development of ...
Y. Gao, L. Huyan, Z. Wu, B. Liu
doaj   +1 more source

Computational Strategies for a System-Level Understanding of Metabolism

open access: yesMetabolites, 2014
Cell metabolism is the biochemical machinery that provides energy and building blocks to sustain life. Understanding its fine regulation is of pivotal relevance in several fields, from metabolic engineering applications to the treatment of metabolic ...
Paolo Cazzaniga   +10 more
doaj   +1 more source

The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters

open access: yesNature Communications, 2023
The piRNA pathway is essential for female fertility in golden hamsters and likely humans, but not in mice. However, the role of individual PIWIs in mammalian reproduction remains poorly understood outside of mice.
Xiaolong Lv   +18 more
doaj   +1 more source

Current Status of Administrative Licensing for Laboratory Animals in Jiangsu Province

open access: yesShiyan dongwu yu bijiao yixue, 2021
This article investigates the administrative licensing data of laboratory animals in Jiangsu Province, summarizes the administrative licenses for laboratory animals in recent years, analyzes the status of the administrative management of laboratory ...
CHEN Lin   +4 more
doaj   +1 more source

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