Results 111 to 120 of about 5,396,651 (301)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MATEC Web of Conferences, 2016 This investigation is to deal with the modeling issue for nonlinear pressurized water reactor cores. Nonlinearity measure with gap metric and T-S fuzzy modeling are exploited to build the fuzzy model of a nonlinear core which approximates this nonlinear ...
Li Gang +4 more
doaj +1 more source
k-core (bootstrap) percolation on complex networks: Critical phenomena and nonlocal effects
, 2006 We develop the theory of the k-core (bootstrap) percolation on uncorrelated random networks with arbitrary degree distributions. We show that the k-core percolation is an unusual, hybrid phase transition with a jump emergence of the k-core as at a first ...
A. Bekessy +8 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
GALFIT-CORSAIR: implementing the core-Sersic model into GALFIT
, 2014 We introduce GALFIT-CORSAIR: a publicly available, fully retro-compatible modification of the 2D fitting software GALFIT (v.3) which adds an implementation of the core-Sersic model.
Bonfini, P.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Unveiling the detailed density and velocity structures of the protostellar core B335
, 2013 We present an observational study of the protostellar core B335 harboring a low-mass Class 0 source. The observations of the H13CO+(J=1-0) line emission were carried out using the Nobeyama 45 m telescope and Nobeyama Millimeter Array.
Kamazaki, Takeshi +4 more
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
, 2014 The model dependence and the symmetry energy dependence of the core-crust transition properties for the neutron stars are studied using three different families of systematically varied extended relativistic mean field model.
Agrawal, B. K. +2 more
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source