Results 201 to 210 of about 77,370 (304)

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

The Journal of Pathology, Volume 269, Issue 2, Page 164-181, June 2026.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen, Satu Tiainen, Jouni Kujala, Linnea Muhonen, Ponnuswamy Mohanasundaram, Tuomas Tikkanen, Ina Pöhner, Tommi Patinen, Simone Adinolfi, Juha P Väyrynen, Päivi Auvinen, Arto Mannermaa, Petri Pölönen, Tuomas Rauramaa, Anna‐Liisa Levonen   +14 more
wiley   +1 more source

Ultrasound-guided core needle biopsy of nodular lesions of the spleen in hematology clinical practice. [PDF]

Oncologist
Broccoli A, Bakken SM, Argnani L, Mazzoni C, Di Benedetto D, Machado M, Masi L, Venturoli N, Agostinelli D, Casadei B, Gugliotta G, Pellegrini C, Stefoni V, Serra C, Zinzani PL.   +14 more
europepmc   +1 more source

Trastuzumab Deruxtecan for HER2‐Low Metastatic Breast Cancer: Practical Considerations for Medical Oncologists and Pathologists in Australia

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 381-391, June 2026.
ABSTRACT Trastuzumab deruxtecan (T‐DXd) is a third‐generation, HER2‐targeting antibody‐drug conjugate that has been shown to significantly prolong overall survival, compared with standard chemotherapy, when used to treat patients who have “HER2‐low” (HER2 immunohistochemistry [IHC] score 1+; or HER2 IHC 2+ plus in situ hybridization‐negative ...
Andrew Redfern, Elgene Lim, Sunil Lakhani, Nirmala Pathmanathan, Sudarsha Selva‐Nayagam, Nicole McCarthy, Belinda Yeo, Benjamin Dessauvagie, Gelareh Farshid   +8 more
wiley   +1 more source

Predictors and nomogram for upstaging to invasive breast carcinoma in ductal carcinoma <i>in situ</i> diagnosed by ultrasound-guided core needle biopsy. [PDF]

Gland Surg
Zhang X, Zhang Y, Zhao J, Wen W, Zhao J, Qiu L.   +5 more
europepmc   +1 more source

Efficacy and safety in synchronous core-needle biopsy and cryoablation for highly suspicious malignant pulmonary nodule. [PDF]

Cancer Imaging
Zhang T, Xu Q, Hu Y, Li H, Du H, Huang Z, Xie S, Yang M, Xu Y, Sun H.   +9 more
europepmc   +1 more source

Real‐world prevalence of PD‐L1 positivity in early‐stage/metastatic triple‐negative breast cancer: primary results and pathology insights from the global retrospective observational VANESSA study

Histopathology, Volume 88, Issue 7, Page 1373-1384, June 2026.
In the real‐world VANESSA study in triple‐negative breast cancer, PD‐L1‐positive prevalence was 38% in early‐stage and 20% in metastatic tumours, lower than in prospective trials. The lower prevalence in smaller versus larger tissue samples and by local versus central assessment underlines the importance of robust PD‐L1 testing to determine eligibility
Corrado D'Arrigo, Sitki Tuzlali, Romualdo Barroso‐Sousa, Nagi S El Saghir, Rebecca Dent, Nataša Medić‐Milijić, Gyungyub Gong, Shahin Sayed, Tu Thai Anh, Alisan Zirtiloglu, Götz Hartleben, Paula Toro, Iman Estaytieh, Enya Weber, Regula Deurloo, João Mouta, Lazar Popovic   +16 more
wiley   +1 more source

Analysis of the risk factors associated with complications following CT-guided percutaneous core needle biopsy of small pulmonary nodules (≤1.5 cm): A single-center retrospective study. [PDF]

Medicine (Baltimore)
Yang J, Mo X, Wu F, Yu H, He P, Du F.
europepmc   +1 more source

A Photothermal‐Responsive PRP‐Loaded Hydrogel Engineered With Composite Nanobottle for Controllable Delivery of Growth Factors and Multifunctional Therapy of Diabetic Wounds

Advanced Science, Volume 13, Issue 25, 4 May 2026.
A photothermal‐responsive engineered platelet‐rich plasma hydrogel (CNB‐ePRP) incorporated with thrombin‐functionalized composite nanobottle was developed, which enables in situ PRP activation, on‐demand growth factor release, multifunctionality, and personalized antimicrobial loading for treatment of diabetic wounds. The CNB‐ePRP hydrogel demonstrated
Wen‐Qiang Qu, Hui‐Yun Gu, Si‐Min Zeng, Chang‐Jiang Liu, Xiao Yan, Ting Pan, Chao Jian, Xian‐Zheng Zhang, Ai‐Xi Yu   +8 more
wiley   +1 more source

Diagnostic yield of fine needle aspiration with simultaneous core needle biopsy for thyroid nodules. [PDF]

J Pathol Transl Med
Hasannia MA, Pourghorban R, Asefi H, Aria A, Nazar E, Ebrahiminik H, Mohamadian A.   +6 more
europepmc   +1 more source